42.8.18 Alkylphosphonous Acids and Derivatives (Update 2025)

Abstract

This is an update to the previous Science of Synthesis contribution (from 2009), describing newly developed methods for the synthesis of alkylphosphonous acids and their derivatives. Various synthetic methodologies have been developed, depending on the structure of the final compound. The majority of examples describe mutual interconversions within the product class, with other transformations having been developed far less extensively.