We introduce the quasi-Hopf superalgebras which are Z 2 -graded versions of Drinfeld's quasi-Hopf algebras. We describe the realization of elliptic quantum supergroups as quasi-triangular quasi-Hopf superalgebras obtained from twisting the normal quantum supergroups by twistors which satisfy the graded shifted cocycle condition, thus generalizing the quasi-Hopf twisting procedure to the supersymmetric case. Two types of elliptic quantum supergroups are defined, that is, the face type B q, (G) and the vertex type A q,p ͓sl(n͉ n)] ͑and A q,p ͓gl(n͉ n)]), where G is any Kac-Moody superalgebra with symmetrizable generalized Cartan matrix. It appears that the vertex type twistor can be constructed only for U q ͓sl(n͉ n) in a nonstandard system of simple roots, all of which are fermionic.