434 Changes in Testicular Arterial Hemodynamics and Semen Quality in Adolescents With Left Sided Varicocele Randomized to Surgery or Observation and Followed Up for 18 Months

Afoko, A.A.; Kogan, M.I.; Siziakin, D.V.; Сизонов, В. В.; Tampuori, J.B.; Asante‐Asamani, Alvin

doi:10.1016/s1569-9056(10)60430-7

Cited by 1 publication

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These findings agreed with Tarhan et al 5 who reported that blood flow parameters (RI_cap) in the left testicular artery decreased significantly after surgery. A study in adolescents reporting with varicocele conducted by Afoko et al 24 reported similar findings. However, the finding in this current study contradicts the findings by Student et al, 9 who reported no significant changes between the mean RI in patients with spermatic vein ligation and spermatic vein preservation before and after surgery.…”

Section: Discussionmentioning

confidence: 54%

“…In this study, the resistive index on the left capsular arteries correlated with sperm concentration and sperm count which agrees with previous literature. 11,24,38 The post-surgery complications are discussed elsewhere. 12 The hypothesis of improvement in vascular supply is limited to mean values and could be a limitation.…”

Section: Discussionmentioning

confidence: 99%

“…36 In another study, Rehman et al 11 conclude that progressive motility of sperms has a correlation with the intraparenchymal blood flow of testes and could be associated with the resistive index of testicular blood flow. Among adolescents with left-sided varicocele, Afoko et al 24 found that resistive index especially in centripetal arteries correlates strongly with semen quality parameters in the surgery group. However, Semiz et al 37 found no significant relationship between the hemodynamic pattern of blood flow and semen analysis parameters.…”

Section: Discussionmentioning

confidence: 99%

“…In this study, the resistive index on the left capsular arteries correlated with sperm concentration and sperm count which agrees with previous literature. 11,24,38…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Changes in testicular arterial hemodynamic, gonadotropin levels, and semen parameters among varicocele patients randomized to varicocelectomy or observed in Tamale, Ghana

2022

View full text Add to dashboard Cite

Objective: A randomized trial to compared testicular blood flow parameters, gonadal hormones, and semen characteristics among three groups; surgery group ( n = 127); observed group ( n = 114); and healthy controls ( n = 33). Methods: The blood flow parameter selected was resistive index (RI) measured using color Doppler ultrasonography. Serum total testosterone, FSH, LH were measured, and semen analysis performed at baseline and repeated 12 months of follow-up. The data was computed using GraphPad Prism (v8.0) at an alpha of 0.05. Results: In the observed group, increased +0.0060 in the right (R_RI) and in the left (L_RI) +0.0026 capsular arteries from baseline measurement to 12 months follow-up. Surgery group, reduced –0.079 in the right (R_RI) and −0.0731 in the left (L_RI) capsular arteries ( p < 0.0001). At 12 months, the changes for both left and right RIcap in the surgery group did not reach the values of the controls. In the surgery group, L_RIcap ( r = −0.63; p < 0.0001) and R_RIcap ( r = −0.49; p = 0.004) correlated with total testosterone, FSH ( r = 0.57; p = 0.001 for left; r = 0.52; p = 0.002 for right), and LH ( r = 0.61; p = 0.0002 for left; r = 0.41; p = 0.020 for right). Furthermore, L_RIcap correlated with changes in sperm count ( r = −0.46; p = 0.008) and sperm concentration ( r = −0.35; p = 0.011) in the surgery group. Conclusion: Microsurgical sub-inguinal varicocelectomy improves blood supply to the testicular tissues evidenced by reduced resistive index in the surgery group. Resistive index in the left capsular artery can be used to evaluate the success of surgery because it correlates with total testosterone, FSH, LH, and semen quality.

show abstract

Section: Discussionmentioning

confidence: 54%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…In this study, the resistive index on the left capsular arteries correlated with sperm concentration and sperm count which agrees with previous literature. 11,24,38…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations