456 Characteristics and Clinical Outcomes in Patients With Spontaneous Coronary Artery Dissection

Tan, Christianne; Dagan, M.; Stehli, Julia; Zaman, Sarah; Duffy, Stephen J.; Kaye, D.

doi:10.1016/j.hlc.2020.09.463

Cited by 1 publication

(4 citation statements)

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“…Those who had SCAD were less likely than patients with typical atherosclerotic AMI to report having high blood pressure, high cholesterol, or diabetes, consistent with past studies. 1 – 4 , 10 , 20 , 48 While patients with SCAD were more likely than patients without SCAD to report obesity, the prevalence rate of 26% is consistent with previous SCAD studies, which have found obesity in 18% to 27%. 10 , 20 , 21 , 51 This rate is also below population rates of 30% in Australia 52 and 40% in the United States.…”

Section: Discussionsupporting

confidence: 89%

“… 1 – 4 , 10 , 20 , 48 While patients with SCAD were more likely than patients without SCAD to report obesity, the prevalence rate of 26% is consistent with previous SCAD studies, which have found obesity in 18% to 27%. 10 , 20 , 21 , 51 This rate is also below population rates of 30% in Australia 52 and 40% in the United States. 53 Indeed, it is possible that the rate of 9% obesity in our non-SCAD sample may represent underreporting.…”

Section: Discussionsupporting

confidence: 89%

“…The cardiovascular risk profile of AMI patients with SCAD in the current study also differed markedly from AMI patients without SCAD, as has been reported elsewhere. Those who had SCAD were less likely than patients with typical atherosclerotic AMI to report having high blood pressure, high cholesterol, or diabetes, consistent with past studies 1–4,10,20,48. While patients with SCAD were more likely than patients without SCAD to report obesity, the prevalence rate of 26% is consistent with previous SCAD studies, which have found obesity in 18% to 27% 10,20,21,51.…”

Section: Discussionsupporting

confidence: 88%

“…Unlike typical AMI, which is generally due to atherosclerosis, SCAD-AMI is nonatherosclerotic and occurs when a coronary vessel develops a hematoma within the arterial wall, which bulges inward obstructing blood flow to the heart 3. Hospital readmission and recurrence are more common post-SCAD than following typical AMI 7–10…”

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confidence: 99%

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Prevalence of Anxiety, Depression, and Distress in SCAD and Non-SCAD AMI Patients

Murphy

Rogerson

Hesselson

et al. 2023

Journal of Cardiopulmonary Rehabilitation and Prevention

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I ncreasing research attention is being paid to the psychosocial consequences of spontaneous coronary artery dissection (SCAD), a cause of acute myocardial infarction (AMI) that is particularly common in young women with few classic cardiac risk factors. [1][2][3][4] Spontaneous coronary artery dissection accounts for up to 35% of AMIs in women aged < 50 yr, 3,4 and is the most common cause of pregnancy-related AMI. 5,6 Unlike typical AMI, which is generally due to atherosclerosis, SCAD-AMI is nonatherosclerotic and occurs when a coronary vessel develops a hematoma within the arterial wall, which bulges inward obstructing blood flow to the heart. 3 Hospital readmission and recurrence are more common post-SCAD than following typical AMI. [7][8][9][10] Studies suggest high levels of anxiety, depression, and stress in survivors of SCAD. 11-15 Indeed, emotional stress is often reported as the precipitating trigger for the acute SCAD event. 3,6,9,11,[16][17][18] Uncertainty and lack of information provision surrounding the diagnosis and optimal management, and the likelihood of recurrence, contribute to the psychosocial sequelae of SCAD. 11,19 Emerging evidence therefore suggests that SCAD may be more stressful than typical AMI.

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