46  How does receiving a survival estimate affect the general health and wellbeing of people living with terminal cancer and their carers? Findings from a systematic review of qualitative experiences

Outcomes of prognostication in people living with advanced cancer: a qualitative study to inform a Core Outcome Set

“…We identified 33 outcomes of prognostication from the interviews, 16 of which were unique to this study and not identified in the systematic review (9). We categorised these outcomes into nine COMET domains, plus one additional domain identified in the literature review (9): spiritual/religious/existential functioning/wellbeing.…”

“…We identified 33 outcomes of prognostication from the interviews, 16 of which were unique to this study and not identified in the systematic review (9). We categorised these outcomes into nine COMET domains, plus one additional domain identified in the literature review (9): spiritual/religious/existential functioning/wellbeing. The resulting ten domains were: (1) mortality/survival; (2) general physiological/clinical outcomes; (3) psychiatric outcomes; (4) spiritual/religious/existential functioning/wellbeing; (5) emotional functioning/wellbeing; (6) social functioning; (7) delivery of care; (8) perceived health status; (9) personal circumstances; (10) societal/carer burden.…”

“…Subsequently, a coding framework was developed. This framework was initially established through the analysis of qualitative studies in a prior systematic review (9) and was informed by the COMET taxonomy outcome domains (10). We further adjusted and expanded upon this framework by incorporating themes that sat outside the existing COMET domains, ensuring a comprehensive capture of data.…”

“…Finally, we compared the identified outcomes against those found in a systematic review of outcomes previously reported in prognostic research with people with advanced cancer (9).…”

“…In alignment with this approach, we conducted a qualitative study within the broader context of our COS development project. This study aimed to explore the perceptions and experiences of patients with advanced cancer, informal caregivers, and clinicians, seeking to identify any additional potential outcomes of prognostication to those identified in the literature (9).…”