469: Diabetes Mellitus Following Heart Transplantation

Nikolaidis, Lazaros A.; Shah, Swetang; McGonagle, Francine; Wong, James

doi:10.1016/j.healun.2009.11.485

Cited by 4 publications

(2 citation statements)

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“…Metabolic derangements such as dyslipidaemia and post-transplant diabetes mellitus (PTDM) are important risk factors for graft fail-ure, coronary events and mortality after organ transplantation [ 13 ]. Other lifestyle-related factors contributing to an increased cardio-vascular risk and functional disability include a reduced exercise capacity [ 14 ], and significant psychosocial issues (i.e., clinical depres-sion, mood disorders with negative affect, demoralization, and coping problems) [ 15 ]. Therefore, lifestyle modification should be an important part of the management of HTx patients.…”

Section: Prevention After Heart Transplantationmentioning

confidence: 99%

Prevention and Rehabilitation After Heart Transplantation: A Clinical Consensus Statement of the European Association of Preventive Cardiology, Heart Failure Association of the ESC, and the European Cardio Thoracic Transplant Association, a Section of ESOT

Simonenko,

Hansen,

Niebauer

et al. 2024

Transpl Int

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Little is known either about either physical activity patterns, or other lifestyle-related prevention measures in heart transplantation (HTx) recipients. The history of HTx started more than 50 years ago but there are still no guidelines or position papers highlighting the features of prevention and rehabilitation after HTx. The aims of this scientific statement are (i) to explain the importance of prevention and rehabilitation after HTx, and (ii) to promote the factors (modifiable/non-modifiable) that should be addressed after HTx to improve patients’ physical capacity, quality of life and survival. All HTx team members have their role to play in the care of these patients and multidisciplinary prevention and rehabilitation programmes designed for transplant recipients. HTx recipients are clearly not healthy disease-free subjects yet they also significantly differ from heart failure patients or those who are supported with mechanical circulatory support. Therefore, prevention and rehabilitation after HTx both need to be specifically tailored to this patient population and be multidisciplinary in nature. Prevention and rehabilitation programmes should be initiated early after HTx and continued during the entire post-transplant journey. This clinical consensus statement focuses on the importance and the characteristics of prevention and rehabilitation designed for HTx recipients.

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Section: Prevention After Heart Transplantationmentioning

confidence: 99%

Prevention and Rehabilitation After Heart Transplantation: A Clinical Consensus Statement of the European Association of Preventive Cardiology, Heart Failure Association of the ESC, and the European Cardio Thoracic Transplant Association, a Section of ESOT

Simonenko,

Hansen,

Niebauer

et al. 2024

Transpl Int

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“…Jako výhodné se jeví po dávání metforminu, při jehož podávání byl u pacientů po ortotopické transplantaci srdce prokázán i snížený výskyt malignit [24]. Je snaha o udržení euglykemie vzhledem k prevenci vývoje vaskulopatie štěpu [12,23].…”

Section: Komplikace Imunosupreseunclassified

The heart transplantation

Špinarová¹,

Špinar²,

Vítovec³

2018

Vnitř Lék

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Interní kardiologická klinika LF MU a FN Brno, pracoviště Bohunice Souhrn Je podán přehled o historii, indikacích a sledování po transplantaci srdce, včetně využití mechanických podpor. Jsou zmíněny možné komplikace v potransplantačním sledování, jako je rejekce, infekce, vaskulopatie štěpu, meta bolické komplikace, hypertenze či malignity. Je shrnuta farmakoterapie, která se užívá zejména k potlačování imu nitní odpovědi organizmu. Transplantace srdce zlepšuje prognózu pacientů se srdečním selháním a rovněž kva litu života.Klíčová slova: imunosuprese -mechanické srdeční podpory -rejekce -terminální srdeční selhání -transplantace srdce The heart transplantation SummaryThe article reviews history, indication and followup after heart transplantation, including the mechanical assist devices. Various complications of posttransplant followup are mentioned, e.g. rejection, infection, vasculopathy, meta bolic disorders, hypertension or malignities. Pharmacotherapy used for immunosuppression is discussed. Heart transplantation improves the prognosis of patients with previous heart failure and also their quality of life.

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