2014
DOI: 10.1017/s1047951114000559
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48th Annual Meeting of the Association for European Paediatric and Congenital Cardiology, with joint sessions with the Japanese Society of Pediatric Cardiology and Cardiac Surgery and Asia-Pacific Pediatric Cardiac Society, Helsinki, Finland, May 21–24, 2014

Abstract: Introduction: RV failure is a significant complication in patients with congenital heart disease with right-sided obstructive lesions, and PH. Effective medical treatment for decompensated RV remains to be elucidated. While ARBs are known to reduce mortality in patients with left side heart failure by inhibiting cardiac remodeling, their effects for RV failure are unknown. Pressure overload stress induces a robust autophagic response and hypertrophic changes in cardiomyocytes. However, previous studies showed … Show more

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