4CPS-103 Pharmacokinetic interaction study of osimertinib and digoxin: a case report

Abstract

and 'Cause of DRP' (k = 0.594 [95% CI: 0.587 -0.601]). The category 'Planned PI' showed substantial agreement (k = 0.638 [95% CI: 0.629 -0.647]). Test-retest reliability achieved an almost perfect agreement for all three main categories: 'Type of DRP' (k = 0.825 [95% CI: 0.734 -0.915]), 'Cause of DRP' (k = 0.896 [95% CI: 0.825 -0.967]) and 'Planned PI' (k = 0.891 [95% CI: 0.819 -0.964]). The median rater-specific contingency coefficient was 0.