4D Sonography in Assessment of Fetal Neurobehavior

Hata, Toshiyuki; Sato, Miki; Kanenishi, Kenji; Hanaoka, Uiko; Tanaka, Hirokazu

doi:10.5005/jp-journals-10009-1234

Cited by 12 publications

(4 citation statements)

References 54 publications

(75 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A tendency toward decreased frequency of facial expressions and movement patterns with increasing gestational age from the second to third trimesters has also been reported [9,[22][23][24][25]. Fetal smiles and spontaneous smiles in neonates are thought to work as a preparation of various facial expressions including social smiles, and the smiles might have the function of facilitating the development of facial muscles especially the zygomatic major muscles [26].…”

Section: Page 7 Ofmentioning

confidence: 89%

Facial Expressions of Fetal Growth Restriction and Appropriate-for-Gestational Age Fetuses Assessed by Four-Dimensional High-Definition Live Ultrasound

Chida¹,

Kikuchi²,

Kanasugi³

et al. 2017

Gynecol Obstet

View full text Add to dashboard Cite

Objective: To determine whether Fetal Growth Restriction (FGR) fetuses have less facial expressions than Appropriate-for-Gestational Age (AGA) counterparts with the assessment by four-dimensional high-definition live (4D HDlive) ultrasound.Methods: 4D HDlive ultrasound examinations of fetal facial expressions were performed on singleton pregnant women between 26 and 39 weeks of gestation. The duration of the 4D HDlive recordings was 15 minutes in all cases. The frequency of seven types of previously-reported facial expressions, or blinking, mouthing, yawning, tongue expulsion, sucking, smiling and scowling, were assessed. Two observers counted the frequencies, and inter-and intra-observer reproducibility was examined. Wilcoxon rank-sum test was used for comparison of FGR and AGA group. Kruskal-Wallis test was used for intra-group significance of frequencies of seven types of fetal facial expressions. P<0.05 was considered significant. Results:In this study, good intra-and inter-class correlation coefficients and intra-and inter-observer agreements were obtained. Thus, measurement values by only one examiner were used for further analysis. The facial expressions of 16 fetuses (FGR: n=8, AGA: n=8) were assessed. We noted a tendency for FGR fetuses to have less facial expressions than AGA counterparts. Although statistically significant inter-group difference was not detected in frequency of any facial expressions, this propensity is conspicuous in smiling (p=0.065) and mouthing (p=0.279). In AGA fetuses, the commonest facial expression was mouthing and was significantly more frequent than blinking (p=0.007), tongue expulsion (p=0.007) and sucking (p=0.002). We also noted a tendency that the frequency of facial expressions declines with fetal maturation. Although no statistically significant difference was shown, this propensity is prominent in mouthing of FGR (p=0.071). Conclusion:4D HDlive ultrasound provides promising modalities in novel evaluative imaging of fetal various facial expressions, and may help to elucidate functional development of Central Nervous System (CNS) and facial expressions both in normal and compromised fetuses.

show abstract

Section: Page 7 Ofmentioning

confidence: 89%

Facial Expressions of Fetal Growth Restriction and Appropriate-for-Gestational Age Fetuses Assessed by Four-Dimensional High-Definition Live Ultrasound

Chida¹,

Kikuchi²,

Kanasugi³

et al. 2017

Gynecol Obstet

View full text Add to dashboard Cite

show abstract

“…7 Now, larger studies are necessary to fully understand the present and future applications of 4-D ultrasound to fetal neurobehavior and neurodevelopment. 68 …”

Section: Discussionmentioning

confidence: 99%

Current status of fetal neurodevelopmental assessment: Four‐dimensional ultrasound study

Hata

2016

J of Obstet and Gynaecol

View full text Add to dashboard Cite

With the latest advent of four-dimensional (4-D) ultrasound, fetal neurobehavioral or neurodevelopmental assessment can be easily and readily performed. Using this technique, typical fetal movements and behavioral patterns have become apparent in all three trimesters of pregnancy. In twin pregnancy, 4-D ultrasound facilitates the precise evaluation of inter-twin contact and intra-pair stimulation. New fetal neurobehavioral assessment tests, such as Kurjak's Antenatal Neurodevelopmental Test and the Fetal Observable Movement System, may reflect the normal and abnormal neurological development of the fetus, and will facilitate more precise assessments of fetal neurobehavior or neurodevelopment, and fetal brain and central nervous system functions. In this review article, I also discuss interesting topics regarding maternal and fetal stress, fetal pain, and fetal consciousness. Four-dimensional ultrasound has opened the door to new scientific fields, such as 'fetal neurology' and 'fetal psychology,' and fetal neurobehavioral science is at the dawn of a new era. Knowledge on fetal neurobehavior and neurodevelopment will be advanced through fetal behavioral research using this technique.

show abstract

“…[1][2][3] With the latest developments in 3D/4D ultrasound technology, HDlive images of the embryo and fetus seem to be more readily discernible than those obtained by conventional 3D/4D ultrasound, because HDlive provides physicians and sonographers with a natural and anatomically realistic appearance. [4][5][6][7][8][9] HDlive is a new surface rendering mode which uses an adjustable light source that facilitates the ability to create lighting and shadowing effects thereby increasing depth perception.…”

Section: Introductionmentioning

confidence: 99%

HDlive Study of Fetal Development and Behavior

Hata¹,

Kanenishi²,

Hanaoka³

et al. 2014

Donald School Journal of Ultrasound in Obstetrics and Gynecology

Self Cite

View full text Add to dashboard Cite

We present the latest HDlive studies of fetal development and behavior during pregnancy. Marked changes of embryonic and fetal development and movement with advancing gestation were noted in the first trimester of pregnancy. Various realistic facial expressions (or facial movements) were recognized in the second and third trimesters. In particular, blinking, mouthing, swallowing, yawning, tongue expulsion, and sucking were clearly depicted. Moreover, various extraordinarily realistic features of fetal emotion-like behavior were identified. HDlive observation of fetal behavior and facial expressions may reflect the normal and abnormal neurological development of the fetus. HDlive may become an important modality in future research on fetal neurobehavioral development and assist in evaluation of the fetal brain function.

show abstract

4D Sonography in Assessment of Fetal Neurobehavior

Cited by 12 publications

References 54 publications

Facial Expressions of Fetal Growth Restriction and Appropriate-for-Gestational Age Fetuses Assessed by Four-Dimensional High-Definition Live Ultrasound

Facial Expressions of Fetal Growth Restriction and Appropriate-for-Gestational Age Fetuses Assessed by Four-Dimensional High-Definition Live Ultrasound

Current status of fetal neurodevelopmental assessment: Four‐dimensional ultrasound study

HDlive Study of Fetal Development and Behavior

Contact Info

Product

Resources

About