“…With the emerge of deep neural networks (DNNs) [ [9] , [10] , [11] , [12] , [13] , [14] ], especially convolutional neural networks (CNNs), they leverage multi-level layer neural networks for representational learning and are widely used for image classification [ 15 , 16 ], object detection [ 17 , 18 ] and semantic segmentation [ 19 ]. Naturally, DNNs are very good at detecting COVID-19 [ [20] , [21] , [22] , [23] , [24] , [25] ]. However, mainly due to lack of interpretability and practical skills, applying DNNs into CXR images for COVID-19 clinical diagnosis has run into obstacles [ 26 ].…”