5-(2,2-Dimethyl-4H-1,3-benzodioxin)methanol: the synthetic precursor to o-formyl-m-hydroxycinnamic acid, the most oxidized salicylaldehyde-type phytotoxin isolated from rice blast fungus, Magnaporthe grisea

Abstract

o-Formyl-m-hydroxycinnamic acid, the most oxidized salicylaldehyde-type phytotoxin isolated from rice blast fungus, Magnaporthe grisea, was synthesized for the first time using 5-(2,2-dimethyl-4H-1,3-benzodioxin)methanol as the starting material, and the proposed structure was confirmed.

Synthetic studies of biologically active natural products contributing to pesticide development

“…3). [30][31][32][33][34][35] Through synthetic studies, it was clarified that the blast fungus produces optically active toxins such as pyriculol and pyricuol under shaking culture conditions, while pyriculariol and dihydropyriculariol resulting from aeration and agitation culture are racemic. 36) Pseudomonas syringae pv.…”