5-30-17 Snoring in Parkinson's disease: Another early sign responsive to L-dopa?

Högl, Birgit; García, S. Beltrán; Gómez-Arévalo, Gonzalo; Scipioni, O.; Gershanik, Oscar S.

doi:10.1016/s0022-510x(97)86454-4

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“…More recent studies demonstrate that obstructive sleep apnoeas are more prevalent in PD patients [26,19] which is probably due to abnormal tone of the muscles surrounding the upper airways [27]. One preliminary anecdotal report [28] and a polysomnographic study [26] have suggested that abnormal muscle tone-induced partial upper airway obstruction during sleep might be levodoparesponsive. However, the initiation of nasal continuous airway pressure (nCAP) treatment in PD patients does not have the same beneficial effects on sleep structure as in patients with obstructive sleep apnoea syndrome alone [26].…”

Section: Respirator Y Disturbancesmentioning

confidence: 99%

Sleep and daytime sleepiness in Parkinson's disease

2003

Swiss Arch Neurol Psychiatr

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Disturbances of sleep and wakefulness in patients with Parkinson's disease (PD) have multiple contributing factors and multiple clinical manifestations.The causes, however, are incompletely understood.Although several of these disturbances have first been described decades ago, awareness for their clinical implications has only increased in recent years, which also prompted new research into the underlying pathomechanisms. The spectrum of sleep and wakefulness disorders in Parkinson's disease comprises sleep fragmentation, microstructural changes, REM-sleep behaviour disorder, periodic limb movements in sleep, respiratory disturbances, autonomic disturbances and daytime sleepiness, which are discussed in detail. Among the contributing factors, dopamine deficiency, motor impairment, the influence of age and comorbid depression, possible genetic influences and the effect of dopaminergic therapy on night sleep and daytime sleepiness are reviewed. Interactions between sleep or sleep deprivation and motor states are discussed (e.g. sleep benefit). One chapter is dedicated to the issue of driving in patients with Parkinson's disease. The final chapter reviews the evaluation of PD patients with sleep disorders and treatment, namely treatment of daytime sleepiness.

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Section: Respirator Y Disturbancesmentioning

confidence: 99%

Sleep and daytime sleepiness in Parkinson's disease

2003

Swiss Arch Neurol Psychiatr

View full text Add to dashboard Cite

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5-30-17 Snoring in Parkinson's disease: Another early sign responsive to L-dopa?

Cited by 1 publication

References 0 publications

Sleep and daytime sleepiness in Parkinson's disease

Sleep and daytime sleepiness in Parkinson's disease

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