5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one Functionalized CuO Nanoparticles: Synthesis, Characterization and Antioxidant activity

Abstract

Naringenin (NaR) is a flavonoid, mostly found in citrus fruit. Its IUPAC name is 5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one. Naringenin is lipophilic in nature and possessing antioxidant property. In present study,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one was incorporated onto CuO nanoparticles (CuO-NPs) for enhancing its antioxidant activity. The CuO-NPs and its functionalized form (CuO-NaR) were characterized by Fourier-transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), Scanning electron microscope (SEM) and Energy dispersive X-ray (EDX) analysis. The CuO-NPs, CuO-NaR and NaR were examined for their comparative antioxidant activities followed by DPPH (2,2-Diphenyl-1-picrylhydrazyl) method. The results revealed that the antioxidant activity of CuO-NaR was enhanced significantly.