5 days of time-restricted feeding increases fat oxidation rate but not affect postprandial lipemia: a crossover trial

Abstract

Studies have revealed that time-restricted feeding affects the fat oxidation rate; however, its effects on the fat oxidation rate and hyperlipidemia following high-fat meals are unclear. This study investigated the effects of 5-day time-restricted feeding on the fat oxidation rate and postprandial lipemia following high fat meals. In this random crossover experimental study, eight healthy male adults were included each in the 5-day time-restricted feeding trial and the control trial. The meals of the time-restricted feeding trial were provided at 12:00, 16:00, and 20:00. The meals of the control trial were provided at 08:00, 14:00, and 20:00. The contents of the meals of both trials were the same, and the calories of the meals met the 24-h energy requirement of the participants. After 5 days of the intervention, the participants consumed high-fat meals on the sixth day, and their physiological changes were determined. The fasting fat oxidation rate (p < 0.001) and postprandial fat oxidation rate (p = 0.019) of the time-restricted feeding trial were significantly higher than those of the control trial. The 24-h energy consumption and postprandial triglyceride, blood glucose, insulin, glycerol, and free fatty acid concentrations of the two trials showed no significant differences (p > 0.05). The results revealed that 5 days of time-restricted feeding effectively increased the fasting and postprandial fat oxidation rate, but it did not affect postprandial lipemia.

A bibliometric analysis and visualization of literature on non-fasting lipid research from 2012 to 2022

“…Nighttime food intake may also increase the risk of dyslipidemia and hence potential of CVD due to postprandial TG metabolic dysfunction ( 70 ). Feeding time restricted within eight hours for five days can increase the fat oxidation rate in both fasting and non-fasting state, but cannot affect postprandial lipemia ( 71 ).…”

Beneficial effects of time-restricted fasting on cardiovascular disease risk factors: a meta-analysis

“…The quality of the 12 selected studies was evaluated using the ROB-2.0 and ROBINS-I evaluation tools [16][17][18][19][20][21][22][23][24][25][26][27]. The quality assessment results are presented in Figs.…”