5-Fluorouracil loaded Eudragit fibers prepared by electrospinning

AC and DC electrospinning of hydroxypropylmethylcellulose with polyethylene oxides as secondary polymer for improved drug dissolution

“…Solventbased electrospinning has been found to be an excellent method also for the preparation of solid dispersions due to the fast and, thus, very efficient amorphization of the drug enclosed in the fibers owing a large surface area Yu et al, 2009). Although various modifications have been published in respect to the ES setup related mostly to the spinneret (e.g., needleless (Molnár and Nagy, 2016), side-by-side or multiaxial electrospinning (Illangakoon et al, 2015;Yang et al, 2016;Yu et al, 2015)), the challenge of increasing the productivity of ES could not have been addressed considering the high output of other fiber formation techniques such as melt blowing (Balogh et al, 2015b). Recent efforts for scaling up of ES combine the electrostatic field with another fiber formation force such as centrifugal force at low (Lomov and Molnár, 2015) and high (Nagy et al, 2015) frequencies, or a blow of air (Balogh et al, 2015c).…”

Electrospun pH-sensitive core–shell polymer nanocomposites fabricated using a tri-axial process

“…These are 309 frequently encountered in traditional single-fluid and coaxial electrospinning [50], but 310 spinning with a pure solvent as the exterior fluid has been shown to reduce incidents 311 of clogging as well as to improve the uniformity of the fibers produced in the latter 312 process [42]. The use of pure solvent as the outer layer will: 1) lubricate the spinneret to retard clinging; 2) prevent the formation of semi-solid substance on the surface of 314 the fluid jets; 3) protect the inner fluid from any environmental fluctuations; and, 4) 315 lead to a longer drawing period under the electrical field, and thus to narrower fibers.…”

Simple Calculations but Amusing Lessons about Teaching Nanotechnology in Higher Education

“…4). For the volume (V) of sphere, it can be calculated according to the equation: V= 4/3πr 3 , where r is the sphere' radius, and the surface can be calculated according to the equation: S=4πr 2 . When two types of particles (one nanoparticles and the other particles can be seen using naked eyes) are prepared with the same volumes (Fig.…”

“…Nanomaterials can find their applications in a wide variety of fields including energy, environment, biomedical engineering, drug delivery and so on [1][2][3][4][5][6]. The nanotechnologies that are applied to create these nanomaterials are not only subjects for researchers majored in this area, but also should be excellent teaching materials for the college and graduate students.…”