5 Iodo-2'-Deoxyuridine in the Treatment of Herpes Zoster.

McCallum, Dugald; Johnston, Elizabeth; Raju, Bharath

doi:10.1111/j.1365-2133.1964.tb15484.x

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1966

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Cited by 8 publications

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“…Several 5-substituted pyrimidine analogues capable of affecting the life cycle of viruses were discovered as highly active antiviral agents. Two such drugs with antiviral properties are 5-iodo-2'-deoxyuridine, discovered in the 1960s as the first agent that is active against Herpes simplex and Varicella zoster viruses [ 2 – 3 ], and 5-vinyl-2'-deoxyuridine, exhibiting high activity against HSV [ 4 – 5 ], which in turn led to studies on the synthesis and biological activity of its analogues.…”

Section: Reviewmentioning

confidence: 99%