“…These steps can be repeated multiple times throughout the day. The video clips, which were developed and validated in psychoneuroimmunology studies in patients with cancer or HIV [ [34] , [35] , [36] , [37] , [38] ], and SCD [ 16 , 39 , 40 ] are platform independent, so that patients can access them anytime anywhere to manage their pain. The clips include a 12-min guided relaxation video (administered at baseline) and 6 additional video clips ranging from 2 to 20 min.…”