51-year old man with tingling, burning and progressive limb weakness

Abstract

Peripheral neuropathy is a common reason for referral to neurology. Chronic acquired demyelinating neuropathies are an important and varied group with overlapping presentations, and may have an immune-mediated cause. Their correct diagnosis is important as they respond to different treatments; timely intervention can prevent irreversible axonal degeneration. We present a case that highlights the approach to an adult presenting with a chronic demyelinating neuropathy.

Chronic inflammatory demyelinating polyneuropathy: a rare cause of falls

“…In practice, it can be difficult to diagnose CIDP with certainty. Initial presentations can be diverse and vague, and there are unusual cases of CIDP which present solely with sensory neurology,5 6 while other cases display significant nerve root hypertrophy leading to compressive pathology 7. While it is important to rule out spinal cord compression in cases of lower limb weakness, primary pathology of the nervous system itself should not merely be an afterthought.…”