52. Outcomes of Women Treated For Popliteal Artery Aneurysms

Abstract

factor beta receptors (TGFBR) 1 and 2. The syndrome, characterized by vascular, skeletal, craniofacial and cutaneous manifestations, predisposes patients to aggressive and widespread vascular disease including aortic root dilation and arterial dissection. Women with LDS are prone to aortic dissection and uterine rupture during pregnancy and the postpartum period. Additionally, aortic disease is believed more aggressive during pregnancy as a result of estrogen-induced changes in the aortic media. We describe the case of a 29 year-old G2P1 woman at 28 weeks gestation presenting with abdominal pain. Workup revealed a 7cm ascending aortic aneurysm and a DeBakey type 1 aortic dissection extending to the aortic bifurcation. Surgical management included concomitant Cesarean-section delivery of a live born premature infant, tubal ligation, ascending aortic replacement with reconstruction of the arch vessels and aortic valve replacement. This is the first reported case of aortic dissection with visceral involvement occurring in a patient with both LDS and pregnancy. This case highlights key concepts regarding etiology and management of acute aortic pathology in the setting of pregnancy and/or LDS including: the effects of pregnancy on aortic pathology, management of aortic pathology during pregnancy, diagnostic criteria for LDS and management of aortic pathology in patients with LDS and CTD.http://dx.