520: Perinatal outcome of pregnancies following in vitro fertilization and ovulation induction

Silberstein, Tali; Levy, Amalia; Harlev, Avi; Saphier, Oshra

doi:10.1016/j.ajog.2013.10.553

Cited by 18 publications

(33 citation statements)

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“…As in our study,Silberstein et al [25] (in a large population based study, IVF; n=1296 and singleton pregnancies conceived spontaneously, n=172 288) pointed out increased gestational diabetes risk in IVF pregnancies than conceived spontaneously (OR=1.77, 95% CI:1.52-2.07, p<0.001).…”

Section: Discussionsupporting

confidence: 59%

Ivf versus spontan singleton pregnancies fetal and maternal outcomes in a tertiary care hospital

Cakar

Yavuz

Kutlu

et al. 2018

ijmsci

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ABSTRACT:Background: We aimed to compare perinatal outcomes of intracytoplasmicsperm injection (ICSI) versus naturally (spontaneously) concieved age and parity matched group of singleton pregnants. Methods: Two hundred and sixteen singleton pregnancies aged between 18-45 years old were included in this study. Among all study group, 106 cases were ICSI pregnancies (study group) and 110 cases were spontaneously concieved singleton pregnancies (control group). Pregnancy outcome parameters were: the incidence of chronic hypertension, preeclampsia, gestational hypertension, placenta previa, placental abruption, preterm birth, intrahepatic cholestasis of pregnancy, gestational diabetes, preterm premature rupture of membranes, caesarean delivery. Results: There were no differences in terms of maternal age, BMI, gravidity, parity, gestational weeks at birth and birth weight between ICSI and spontaneously concieved pregnancy groups. Placental abruption, gestational diabetes and cesarean section rates were significantly higher in ICSI pregnancies than spontaneously conceived pregnancies (4.7% vs 0%, 21.7% vs 11.8% and 82.1% vs 68.2%, respectively). There wereno statistically significant differences in terms of chronic hypertension, preeclampsia, gestational hypertension, preterm labor, placenta previa, intrahepatic cholestasis of pregnancy, preterm and term premature rupture of the membranes. Conclusion: ICSI pregnancies have higher adverse perinatal outcomes than spontaneously conceived singleton pregnancies which were matched with age and parity. That's why ICSI pregnancies should be given a detailed counseling about the adverse perinatal outcomes and should be followed up more carefully through the pregnancy.

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Section: Discussionsupporting

confidence: 59%

Ivf versus spontan singleton pregnancies fetal and maternal outcomes in a tertiary care hospital

Cakar

Yavuz

Kutlu

et al. 2018

ijmsci

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“…Increased rates of pre‐eclampsia, FGR, and preterm delivery support the hypothesis of placentation anomalies and placental insufficiency as the pathophysiologic basis for adverse perinatal outcomes. Moreover, placentation anomalies have been reported to be one of the consequences of fertility treatments . Estradiol elevation during fertility treatment has been associated with pregnancy adverse events related to anomalous placentation owing to estradiol being the main hormone that affects endometrial growth and preparation for decidualization .…”

Section: Discussionmentioning

confidence: 99%

“…Significantly higher rates of hypertensive disorders, premature rupture of membranes, cesarean delivery, preterm and very preterm delivery, low and very‐low delivery weight, and fetal growth restriction (FGR) were reported among pregnancies following ART . Moreover, pregnancies conceived via in vitro fertilization (IVF) and ovulation induction have been reported to have a higher risk of adverse perinatal outcomes; the highest adverse event rates were reported for IVF, followed by ovulation induction, with the lowest recorded for spontaneous conception, with a linear relationship described for this association …”

Section: Introductionmentioning

confidence: 99%

The effect of fertility treatment on adverse perinatal outcomes in women aged at least 40 years

Harlev

Walfisch

Oran

et al. 2017

Intl J Gynecology & Obste

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Objective: To compare perinatal outcomes between spontaneous conception and assisted reproductive technologies (ART) among patients of advanced maternal age. Methods:The present retrospective study included data from singleton pregnancies of women aged at least 40 years who delivered between January 1, 1991, and December 31, 2013, at Soroka University Medical Center, Beer Sheva, Israel.Demographic, obstetric, and perinatal data were compared between pregnancies conceived with ART (in vitro fertilization [IVF] or ovulation induction) and those conceived spontaneously. Multiple regression models were used to define independent predictors of adverse outcomes. Conclusions: Among patients of advanced maternal age, ART were independently associated with increased FGR and preterm delivery rates compared with spontaneous pregnancies; perinatal mortality was comparable. K E Y W O R D S

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“…Risks for an Apgar score <7 among IVF singletons compared with the total population have both been reported to be both increased and not increased (8)(9)(10)(11). None of these studies have distinguished between different gestational ages or used matched populations.…”

mentioning

confidence: 97%

Risk of poor neonatal outcome at term after medically assisted reproduction: a propensity score–matched study

Ensing

Abu‐Hanna

Roseboom

et al. 2015

Fertility and Sterility

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520: Perinatal outcome of pregnancies following in vitro fertilization and ovulation induction

Cited by 18 publications

References 0 publications

Ivf versus spontan singleton pregnancies fetal and maternal outcomes in a tertiary care hospital

Ivf versus spontan singleton pregnancies fetal and maternal outcomes in a tertiary care hospital

The effect of fertility treatment on adverse perinatal outcomes in women aged at least 40 years

Risk of poor neonatal outcome at term after medically assisted reproduction: a propensity score–matched study

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