528 the Role of Natural Compound D161 in Neurogenic Inflammation

Lupu, Andreea-Roxana; Cremer, Lidia; Kerek, Franz; Călugăru, A; Barzu, N.S.; Coman, Cristin; Flonta, Maria-Luiza; Szégli, G

doi:10.1016/s1090-3801(09)60531-0

Cited by 2 publications

(3 citation statements)

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“…Various groups work intensively on assessing the very complex interactions between living tissue and APP. They found growing evidence for the beneficial potential of plasma therapy in medicine, especially in dermatology, cancer therapy, and dentistry . However, it is still not entirely known how plasma affects biological samples and which mechanisms underlie such effects.…”

Section: Introductionmentioning

confidence: 99%

A μs‐Pulsed Dielectric Barrier Discharge Source: Physical Characterization and Biological Effects on Human Skin Fibroblasts

Tiede

Hirschberg

Viöl

et al. 2016

Plasma Processes & Polymers

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As the field of plasma medicine eventually develops, safety aspects of biocompatible plasma sources are becoming ever more important for a safe usage of plasma devices as medical instruments. In this study physical and biological safety parameters of an atmospheric pressure dielectric barrier discharge (DBD) source with a phosphate buffered saline-electrode (PBS-electrode) were analyzed. For a general characterization of this DBD device the dissipated power, rotational and electron energies, and reactive species were investigated. Cell vitality tests of human skin fibroblasts treated with the device directly and indirectly were performed using an MTS assay. Additionally, applying a host cell reactivation (HCR) assay fibroblasts' DNA repair capacity for plasma-induced damages was examined. Our risk assessments indicate that this DBD device can be used safely in therapeutic applications.A ms-pulsed dielectric barrier discharge source . . . Plasma Process. Polym. 2016, 13, 775-787 ß

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Section: Introductionmentioning

confidence: 99%

A μs‐Pulsed Dielectric Barrier Discharge Source: Physical Characterization and Biological Effects on Human Skin Fibroblasts

Tiede

Hirschberg

Viöl

et al. 2016

Plasma Processes & Polymers

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“…[35] Also, the transfer of plasma to internal tissues and deep tumors is a challenging issue for scientists. [36,37] CAP and PAM are effective treatments for cancer cells of the brain, [24,38] lung, [39] gastric, [40] liver, [41] pancreatic, [42] colon, [43] and skin [44] under in-vitro conditions. It was demonstrated the CAP-induced dosedependent cell death.…”

Section: Introductionmentioning

confidence: 99%

“…CAP and PAM are effective treatments for cancer cells of the brain, [ 24,38 ] lung, [ 39 ] gastric, [ 40 ] liver, [ 41 ] pancreatic, [ 42 ] colon, [ 43 ] and skin [ 44 ] under in‐vitro conditions. It was demonstrated the CAP‐induced dose‐dependent cell death.…”

Section: Introductionmentioning

confidence: 99%

Direct cold atmospheric plasma and plasma‐activated medium effects on breast and cervix cancer cells

Jezeh

Tayebi

Khani

et al. 2020

Plasma Processes & Polymers

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In this study, the effects of cold plasma and plasma-activated medium (PAM) are investigated through different treatment times, different intervals between treatment and analysis, and synthesis of helium gas and helium + 0.5% oxygen. The viability of two cancer cell lines including Hela and MDA-MB-231, which are related to cervix and breast cancers, respectively, is investigated using the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide assay. To study the effect of plasma on normal cells, the corresponding method is used for examination of the normal human fibroblasts. H 2 O 2 showed a higher concentration after direct-plasma treatment than PAM treatment. Caspase 3, caspase 8, and Bax proteins and the relative Bax/Bcl-2 ratio are compared in both the direct-plasma and PAM methods. The results show that the expression level of apoptotic proteins caspase 3 and caspase 8 in direct-plasma treatment is higher than that in PAM treatment, and the level of relative Bcl-2/Bax ratio is increased, demonstrating the induction of the apoptosis mechanism.

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528 the Role of Natural Compound D161 in Neurogenic Inflammation

Cited by 2 publications

References 0 publications

A μs‐Pulsed Dielectric Barrier Discharge Source: Physical Characterization and Biological Effects on Human Skin Fibroblasts

A μs‐Pulsed Dielectric Barrier Discharge Source: Physical Characterization and Biological Effects on Human Skin Fibroblasts

Direct cold atmospheric plasma and plasma‐activated medium effects on breast and cervix cancer cells

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