559 Gender reassignment surgery – a 13 year review of surgical outcomes

Rossi, N; Hintz, F.; Krege, S.; Rübben, H.; Vom, Dorp F.; Hess, Jason

doi:10.1016/s1569-9056(13)61042-8

Cited by 3 publications

(5 citation statements)

References 16 publications

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“…In 2 of these patients, a rectovaginal fistula became evident, requiring fistulectomy and colonic transit deviation. This is consistent with current literature, in which rectal injury is reported in 0.4-4.5 percent of patients (4,5,(8)(9)(10)(11)(12)(13). Goddard et al suggested carefully checking for enterotomy after prostate and bladder mobilization by digital rectal examination (4).…”

Section: Postoperative Resultssupporting

confidence: 88%

“…The mean age of transsexual women who underwent GAS in our study was 32.2 years (range 18-61 years), which is lower than the mean age of patients in studies found in the literature. Two studies indicated that the mean ages of patients at time of GAS were 36.7 years and 41 years, respectively (4,5). Another study reported a mean age at time of GAS of 36 years and found there was a significant decrease in age at the time of GAS from 41 years in 1994 to 35 years in 2015 (7).…”

Section: Postoperative Resultsmentioning

confidence: 99%

“…Neovagina introital stricture was observed in 33 patients (15.4 percent) in our study and impedes the possibility of neovaginal penetration and/or adversely affects sexual life quality. In the literature, the reported incidence of introital stenosis range from 6.7 to 14.5 percent (4,5,8,9,(11)(12)(13). According to Hadj-Moussa et al (18) a regimen of postoperative prophylactic dilation is crucial to minimize the development of this outcome.…”

Section: Postoperative Resultsmentioning

confidence: 99%

“…At our institution, we perform the classic penile inversion vaginoplasty (PIV), with an inverted penis skin flap used as the lining for the neovagina. Studies have demonstrated that GAS for the management of GD can promote improvements in mental health and social relationships for these patients (2)(3)(4)(5). It is therefore imperative to understand and establish best practice techniques for this patient population (2).…”

Section: Introductionmentioning

confidence: 99%

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Male-to-Female Gender-Affirming Surgery: 20-Year Review of Technique and Surgical Results

et al. 2021

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Purpose: Gender dysphoria (GD) is an incompatibility between biological sex and personal gender identity; individuals harbor an unalterable conviction that they were born in the wrong body, which causes personal suffering. In this context, surgery is imperative to achieve a successful gender transition and plays a key role in alleviating the associated psychological discomfort. In the current study, a retrospective cohort, we report the 20-years outcomes of the gender-affirming surgery performed at a single Brazilian university center, examining demographic data, intra and postoperative complications. During this period, 214 patients underwent penile inversion vaginoplasty.Results: Results demonstrate that the average age at the time of surgery was 32.2 years (range, 18–61 years); the average of operative time was 3.3 h (range 2–5 h); the average duration of hormone therapy before surgery was 12 years (range 1–39). The most commons minor postoperative complications were granulation tissue (20.5 percent) and introital stricture of the neovagina (15.4 percent) and the major complications included urethral meatus stenosis (20.5 percent) and hematoma/excessive bleeding (8.9 percent). A total of 36 patients (16.8 percent) underwent some form of reoperation. One hundred eighty-one (85 percent) patients in our series were able to have regular sexual intercourse, and no individual regretted having undergone GAS.Conclusions: Findings confirm that it is a safety procedure, with a low incidence of serious complications. Otherwise, in our series, there were a high level of functionality of the neovagina, as well as subjective personal satisfaction.

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Section: Postoperative Resultssupporting

confidence: 88%

Section: Postoperative Resultsmentioning

confidence: 99%

Section: Postoperative Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Male-to-Female Gender-Affirming Surgery: 20-Year Review of Technique and Surgical Results

et al. 2021

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“…There are virtually no data regarding patient-derived study priorities (110,111). There are small-scale studies on the topic of genderaffirming hormone outcomes, including a series that examined the degree of breast development and time to cessation of menses.…”

Section: Gaps In Patient-centered and Comparative Efficacy Studiesmentioning

confidence: 99%

Research gaps in medical treatment of transgender/nonbinary people

Safer¹

2021

Journal of Clinical Investigation

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Priorities for transgender medical and healthcare research

Feldman

Brown

Deutsch

et al. 2016

Current Opinion in Endocrinology, Diabetes &Amp; Obesity

124

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Purpose of Review Transgender individuals experience unique health disparities but are the subject of little focused health research. This manuscript reviews current literature on transgender medical and mental health outcomes and proposes research priorities to address knowledge gaps. Recent Findings Published research in transgender health care consists primarily of case reports, retrospective and cross-sectional studies, involving largely European settings. Challenges to US-based transgender health research include a diverse population where no single center has sufficient patient base to conduct clinical research with statistical rigor. Treatment regimens are heterogeneous and warrant study for best practices. Current research suggests increased mortality and depression in transgender individuals not receiving optimal care, and possibly a modest increase in cardiovascular risk related to hormone therapy. Current evidence does not support concerns for hormone related malignancy risk. Summary The priorities for transgender medical outcomes research should be to determine health disparities and co-morbid health conditions over the life span, along with the effects of mental health, medical, and surgical interventions on morbidity and mortality. Specific outcomes of interest based on frequency in the literature, potential severity of outcome, and patient-centered interest, include affective disorders, cardiovascular disease, malignancies, fertility, and time-dose related responses of specific interventions.

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559 Gender reassignment surgery – a 13 year review of surgical outcomes

Cited by 3 publications

References 16 publications

Male-to-Female Gender-Affirming Surgery: 20-Year Review of Technique and Surgical Results

Male-to-Female Gender-Affirming Surgery: 20-Year Review of Technique and Surgical Results

Research gaps in medical treatment of transgender/nonbinary people

Priorities for transgender medical and healthcare research

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