567: ABO-Incompatible paediatric heart transplantation: The first 10 years

Dipchand, Anne I.; West, Lori J.; Bar-Ziv, Stacey M. Pollock; Manlhiot, Cedric; VanderVliet, M.; McCrindle, B.W.

doi:10.1016/j.healun.2006.11.592

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“…7,13,14 These favorable results led to the acceptance of ABO-I organ transplantation in 2001 by the UNOS, which governs transplantation in the United States. Our study shows that although the number of infants listed as eligible for ABO-I transplant in the United States has steadily increased, such that approximately half of all infants listed for heart transplant are now eligible for an ABO-I organ, the number of ABO-I heart transplants performed in the United States remains low.…”

Section: Discussionmentioning

confidence: 99%

Effect of ABO-Incompatible Listing on Infant Heart Transplant Waitlist Outcomes: Analysis of the United Network for Organ Sharing (UNOS) Database

Everitt

Donaldson

Casper

et al. 2009

The Journal of Heart and Lung Transplantation

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Section: Discussionmentioning

confidence: 99%

Effect of ABO-Incompatible Listing on Infant Heart Transplant Waitlist Outcomes: Analysis of the United Network for Organ Sharing (UNOS) Database

Everitt

Donaldson

Casper

et al. 2009

The Journal of Heart and Lung Transplantation

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ABO-incompatible heart transplantation: crossing the immunological barrier

Gambino

Torregrossa²,

Angelini³

et al. 2008

Journal of Cardiovascular Medicine

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Due to the shortage of organ donors, heart transplantation cannot be offered to many infants with end-stage heart failure; this issue leads to mortality rates of 30-50% in patients in the paediatric age group awaiting operation. ABO-incompatible heart transplantation has been performed safely with no particular or invasive preparatory procedures other than plasma exchange during cardiopulmonary bypass for removing preformed antibodies, with no reports of hyperacute rejection. We report our first clinical experience of heart transplantation on a 2-month-old-infant (blood group O), diagnosed with intracardiac tumour, in which the donor was a 19-day-old newborn of blood group A. Sharing the know-how about ABO-incompatible heart transplantation in newborns and infants awaiting transplantation will help in decreasing mortality among this group of patients.

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567: ABO-Incompatible paediatric heart transplantation: The first 10 years

Cited by 2 publications

References 0 publications

Effect of ABO-Incompatible Listing on Infant Heart Transplant Waitlist Outcomes: Analysis of the United Network for Organ Sharing (UNOS) Database

Effect of ABO-Incompatible Listing on Infant Heart Transplant Waitlist Outcomes: Analysis of the United Network for Organ Sharing (UNOS) Database

ABO-incompatible heart transplantation: crossing the immunological barrier

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