57-jährige Patientin mit Kollaps beim Autofahren

Hempfling, W.; Rust, Christian; Fürst, H.; Aust, Daniela E.; Reiser, Maximilian; Jacob, K.; Engelhardt, D.

doi:10.1007/s001080100440

Cited by 2 publications

(1 citation statement)

References 13 publications

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“…[3] seltene neuroendokrine Tumore des Gastrointestinalstraktes. In 90-96 % handelt es sich um gutartige Raumforderungen [2][3][4][5]. Der Altersgipfel liegt im 5.…”

Section: Diskussionunclassified

Rezidivierende zerebrale Krampfanfälle unklarer Genese

Krauß¹,

Berkermann²,

Ghadimi³

et al. 2016

Dtsch med Wochenschr

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History and admission findings | A 41year old woman presented at our internistic clinic after treatment by an emergency doctor because of confusion and amnesia accompanied by a hypoglycaemic episode while driving her car. Only by giving continuous glucose intravenously a stable clinical state could be achieved. In her medical history she took Lamotrigin for 12 years since she had seizures of unknown aetiology. 16 years ago she had similar sudden attacks with confusion and hypoglycaemia. At that time thorough diagnostics at the clinic for internal medicine did not reveal any evidence for hyperinsulinaemia. While taking Lamotrigin the patient had no seizures or similar symptoms for 12 years. Treatment and course | In the present case we detected a tumor in the pancreas and a two-fold increased insulin secretion. Histopathological work-up of the removed tissue confirmed the suspected diagnosis of insulinoma. Postoperatively, Lamotrigin treatment was terminated. Since then the patient remained asymptomatic.

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“…[3] seltene neuroendokrine Tumore des Gastrointestinalstraktes. In 90-96 % handelt es sich um gutartige Raumforderungen [2][3][4][5]. Der Altersgipfel liegt im 5.…”

Section: Diskussionunclassified

Rezidivierende zerebrale Krampfanfälle unklarer Genese

Krauß¹,

Berkermann²,

Ghadimi³

et al. 2016

Dtsch med Wochenschr

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Invasive Diagnostik bei Insulinomen des Pankreas

et al. 2009

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Insulinomas are the most common cause for hypoglycemia with endogenous hyperinsulinism. Insulinomas are the most frequent endocrine tumor of the pancreas and 10% occur as multiple tumors (e.g. multiple endocrine neoplasia type I) or in rare cases as islet cell hyperplasia. A further 10-15% of insulinomas are malignant. Non-invasive imaging modalities, such as computed tomography (CT), magnetic resonance imaging (MRI), ultrasonography (US) and somatoreceptor scintigraphy (SRN) show a lower sensitivity for detection and localization of tumors, because in many cases insulinomas are smaller than 2 cm in size. Invasive pre-operative diagnostic procedures, such as transhepatic peripancreatic venous blood sampling (TPVB) and the intra-arterial calcium stimulation test (ASVS) are much more time-intensive compared to CT, MRI and US with an examination time of 2-3 h but achieve a more exact pre-operative detection and localization with sensitivities mostly greater than 95% and are therefore the diagnostic methods of choice.

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57-jährige Patientin mit Kollaps beim Autofahren

Cited by 2 publications

References 13 publications

Rezidivierende zerebrale Krampfanfälle unklarer Genese

Rezidivierende zerebrale Krampfanfälle unklarer Genese

Invasive Diagnostik bei Insulinomen des Pankreas

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