(5S)-5-Benzylswainsonines as potent and selective inhibitors of Golgi α-mannosidase II: synthesis, enzyme evaluation and molecular modelling

Kalník, Martin; Gabko, Peter; Kóňa, Juraj; Šesták, Sergej; Moncoľ, Ján; Bella, Maroš

doi:10.1016/j.bioorg.2024.107578

Bioorganic Chemistry

2024

DOI: 10.1016/j.bioorg.2024.107578

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(5S)-5-Benzylswainsonines as potent and selective inhibitors of Golgi α-mannosidase II: synthesis, enzyme evaluation and molecular modelling

Martin Kalník,

Peter Gabko,

Juraj Kóňa

et al.

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Structure-guided design of C3-branched swainsonine as potent and selective human Golgi α-mannosidase (GMII) inhibitor

Koemans,

Bennett,

Ferraz

et al. 2024

Chem. Commun.

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Structure-guided design of C3-branched swainsonine as potent and selective human Golgi α-mannosidase (GMII) inhibitor

Koemans,

Bennett,

Ferraz

et al. 2024

Chem. Commun.

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show abstract

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(5S)-5-Benzylswainsonines as potent and selective inhibitors of Golgi α-mannosidase II: synthesis, enzyme evaluation and molecular modelling

Cited by 1 publication

References 49 publications

Structure-guided design of C3-branched swainsonine as potent and selective human Golgi α-mannosidase (GMII) inhibitor

Structure-guided design of C3-branched swainsonine as potent and selective human Golgi α-mannosidase (GMII) inhibitor

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