6‐Chloro‐1‐Hexene and 8‐Chloro‐1‐Octene

Abstract

6‐chloro‐1‐hexene and 8‐chloro‐1‐octene intermediate: Allylmagnesium bromide reactant: allyl bromide (181.60 g, 1.50 mol) product: 6‐Chloro‐1‐hexene reactant: 1‐bromo‐3‐chloropropane (150.00 g, 0.95 mol) reactant: 1‐bromo‐5‐chloropentane (88.37 g, 0.47 mol) product: 8‐chloro‐1‐octene

Side-chain Modifications of Highly Functionalized 3(2H)-Furanones

“…At this point, we elongated the side chain of compound 8 with allylmagnesium bromide [ 15 ] ( Scheme 6 ) obtaining compound 9 in 52% yield. The product seems to be homogenous either by TLC and column chromatography, however the 13 C-NMR spectrum shows duplicates for seven out of the expected 14 signals, suggesting the formation of two diastereoisomers.…”