6-phytase and/or endo-β-xylanase and -glucanase reduce weaner piglet´s diarrhea and improve bone parameters

Effects of phytase and 25‐hydroxyvitamin D3 supplementation on growth performance and bone development in weaned piglets in Ca‐ and P‐deficient dietary

“…Supplementation with different doses of Phy in the diet of weaned piglets would improve growth performance and bone development, which has been widely reported. 1,14,23 Phy can improve the performance of weaned piglets and the average daily gain of fattening pigs on low-Ca/P diets. 24 HyD benefited from Ca/P digestibility.…”

“…Brandão Melo et al . also demonstrated supplementation with Phy with or without carbohydrase in diets with reduced nutritional levels could increase nutrient uptake, reduce diarrhea incidence, and improve bone parameters in weaned piglets 1 …”

“…Phosphorus (P) is an essential mineral element and is involved in a variety of body functions in humans and animals, including cell differentiation, plasma membrane structure, maintenance of acid-base balance, and mineralization of the bone matrix. 1 The majority of P is bound in phytate in diets of plant origin, but pigs cannot produce endogenous phytase (Phy) that hydrolyzes phytate P. Therefore, P has low bioavailability in pigs, although they receive some contribution from endogenous production of Phy by gut microbiota. 2,3 On the other hand, Phy could decrease the availability of other dietary nutrients, including protein, starch and lipids, 4 resulting in discharge of the undigested nutrients to the environment.…”

“…17 Brandão Melo et al also demonstrated supplementation with Phy with or without carbohydrase in diets with reduced nutritional levels could increase nutrient uptake, reduce diarrhea incidence, and improve bone parameters in weaned piglets. 1 Vitamin D status is also a critical factor in bone development. Vitamin D 3 playwe biological roles needs to be converted into 25-hydroxycholecalciferol D3 (25-OH-D3, HyD) by 25-hydroxylase in the liver.…”

Effects of supplementation of high‐dosing Trichoderma reesei phytase in the corn‐wheat‐soybean meal‐based diets on growth performance, nutrient digestibility, carcass traits, faecal gas emission, and meat quality in growing‐finishing pigs

“…The exogenous phytase is used to alleviate the anti-nutritional effects of phytate as well as to reduce the nutrient ingredients supplementation to the diet of pigs. This will consequently lead to a reduction in feed-related production costs (Melo et al, 2020) and reduce the excretion of nutrient ingredients through the enhancement of nutrient digestibility (Rutherfurd et al, 2014). Phytase is an enzyme produced by bacteria, fungi and yeasts, which hydrolyses phytate and promote releasing nutrients that bind with phytate (Cowieson et al, 2017).…”