61  Effect of branched-chain amino acid and N-acetylcysteine supplementation post-exercise on muscle mTOR signaling in exercising horses

Equine mesenchymal stem cell derived extracellular vesicle immunopathology biomarker discovery

“…The pathways remain diverse, but many of them, such as the TGF‐beta signalling pathway, lysine degradation, ECM‐receptor interactions, adherent junctions and focal adhesions, are involved in the control of normal and OA joints (Kang et al., 2016 ; Mok & Urschel, 2020 ; Shen et al., 2014 ; Van Der Kraan, 2018 ). Other pathways and their roles, including mTOR and HIF‐1 signalling pathways, have been investigated in exercised and sepsis‐related laminitis equine subjects, respectively (Hauss et al., 2021 ; Pawlak et al., 2014 ). Renal cell carcinoma, thyroid cancer, endometrial cancer and other cancer pathways have also been reported in equines (Chaffin et al., 1990 ; Dalefield & Palmer, 1994 ; Wise et al., 2009 ).…”