644 Genome-Wide Association and High Throughput Genotype Imputation Studies Confirm a Susceptibility Locus to HCV Infection on 6P22.1–P21.31

Campo, J.A. Del; Maraver, M.; Pardo, Belén G.; Grande, Lourdes; Diago, M.; Carmona, Isabel; Andrade, Rízia da Silva; Rivero, M.C.; Velasco, Javier; Sáez, María Eugenia; Ramírez-Lorca, Reposo; Morón, Francisco Jesús; Carrasco, José Miguel; Salinas, Ana; Molero, Eva; Royo, José Luis; Moréno, Carole; Pérez, Alicia González; Gayán, Javier; Real, Luis Miguel; Ruíz, Agustín; Romero‐Gómez, Manuel

doi:10.1016/s0168-8278(10)60646-0

Journal of Hepatology

2010

DOI: 10.1016/s0168-8278(10)60646-0

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644 Genome-Wide Association and High Throughput Genotype Imputation Studies Confirm a Susceptibility Locus to HCV Infection on 6P22.1–P21.31

J.A. Del Campo¹,

M. Maraver²,

Belén G. Pardo³

et al.

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2011

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“…Prevalence of different genotypes CC, CT and TT in patients with sustained virological response (SVR) belonging to different cohorts(132) and(133) …”

mentioning

confidence: 99%

Genes and hepatitis C: susceptibility, fibrosis progression and response to treatment

Romero–Gómez

Mohamed

Ruiz³

et al. 2011

Liver International

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Hepatitis C virus contact and infection show three different phenotypes: spontaneous viral clearance (SVC), chronic hepatitis C (CHC) and sustained virological response (SVR) following antiviral treatment. Many factors, including genetics, influence the evolution of these three phenotypes. We performed a literature search (PubMed) up to 31 January 2010 without language restriction to identify relevant studies on genes and hepatitis C. Additional studies were sought by reviewing the reference lists of the identified articles. Meta-analysis (using Meta-disk 1.4) was conducted to evaluate the association of single nucleotide polymorphism (SNP) in the IL28B region and SVR. The candidate gene approach showed strong relationships between human leucocyte antigen class II (DQB1 Ã 0301 and DRB1 Ã 1101) and SVC. A cirrhosis risk score involving 7 SNPs has been validated recently. The set of odds ratios of studies demonstrated an association between SNP (rs12987960/ rs8099917) in the IL28B and SVR in CHC treated with peginterferon plus

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“…Prevalence of different genotypes CC, CT and TT in patients with sustained virological response (SVR) belonging to different cohorts(132) and(133) …”

mentioning

confidence: 99%

Genes and hepatitis C: susceptibility, fibrosis progression and response to treatment

Romero–Gómez

Mohamed

Ruiz³

et al. 2011

Liver International

View full text Add to dashboard Cite

show abstract

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644 Genome-Wide Association and High Throughput Genotype Imputation Studies Confirm a Susceptibility Locus to HCV Infection on 6P22.1–P21.31

Cited by 1 publication

References 0 publications

Genes and hepatitis C: susceptibility, fibrosis progression and response to treatment

Genes and hepatitis C: susceptibility, fibrosis progression and response to treatment

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