66  In vitro comparison of six raw materials on gastric ecosystem activity and acidity

Julliand, S.; Julliand, V.; Grimm, Pauline

doi:10.1016/j.jevs.2021.103529

Cited by 1 publication

(5 citation statements)

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“…11 This acid buffering capacity of alfalfa can also contribute to maintaining a higher pH despite the acidic secretions and strong fermentations in the gastric environment, as illustrated in vitro and in vivo. 12,13 The prevalence of GGD scores ≥2 at D0 was lower than we expected. Therefore, the size of the control and alfalfa groups with ulcerated horses was small (N = 6 per group).…”

Section: Discussionmentioning

confidence: 50%

“…In vitro, 2.6 to 4.3 times more hydrochloric acid is needed to decrease the pH from 7.0 to 4.0 when dehydrated alfalfa is added to distilled water compared with corn, oats, and barley 11 . This acid buffering capacity of alfalfa can also contribute to maintaining a higher pH despite the acidic secretions and strong fermentations in the gastric environment, as illustrated in vitro and in vivo 12,13 …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Among plants commonly fed to horses, alfalfa is one of the most effective antacids 11 . In a gastric environment, alfalfa maintains a higher pH in vivo 12 and in vitro 13 . Feeding alfalfa hay to yearlings for 28 days is associated with a lower ulcer severity score than feeding costal Bermudagrass hay 14 .…”

Section: Introductionmentioning

confidence: 99%

“… 11 In a gastric environment, alfalfa maintains a higher pH in vivo 12 and in vitro. 13 Feeding alfalfa hay to yearlings for 28 days is associated with a lower ulcer severity score than feeding costal Bermudagrass hay. 14 Feeding alfalfa forage‐based feeds for 42 days reduces ulcer severity scores in both the glandular and nonglandular areas in horses not at work.…”

Section: Introductionmentioning

confidence: 99%

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Effect of diet composition on glandular gastric disease in horses

Julliand

Buttet²,

Hermange³

et al. 2023

Veterinary Internal Medicne

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Background Nutritional factors are suggested to influence the incidence and severity of glandular gastric disease (GGD) in horses. Objectives To retrospectively assess whether dietary fermentable carbohydrates increase the severity of GGD and to prospectively evaluate whether the partial substitution of concentrates by dehydrated alfalfa would decrease GGD severity scores. Animals In total, 82 trotters from 4 training centers exercised ≥5 days/week. Methods Multicenter retrospective observational study, and prospective 2‐arm randomized trial. Glandular mucosae were observed by gastroscopy and scored (0‐4 severity scale) at day 0 (D0). Biochemical composition of the diet fed was compared between ulcerated and nonulcerated groups. After D0, horses either received the same diet (control, n = 41) or pelleted dehydrated alfalfa substituting 50% concentrates (alfalfa, n = 41). Glandular scores were recorded in both groups after 21 (D21) and 42 days (D42). The first end point was a successful outcome, defined as a horse with a glandular score of 2 to 4 on D0, decreasing to a score of 0 to 1 on days 21 or 42. Results Horses scored 0 to 1 at D0 ingested more (P = .01) soluble sugars from concentrates than those scored 2 to 4 before D0 (77.5 g/kg BW; 95% confidence interval [CI]: 71.1‐84.0, vs 59.1 g/kg BW; 95% CI: 48.0‐70.3), whereas starch intake did not differ between groups (P = .24). Among horses scored 2 to 4 at D0, fewer were scored 2 to 4 in the alfalfa group (1 out of 6) compared with the control group (6 out of 6) at D42 (P = .02). Clinical success was 47.7 times more likely in horses fed alfalfa compared with horses in the control group (95% CI: 1.6‐1422.8). Conclusion and Clinical Importance Relationships were found between diet composition and integrity of the glandular mucosa. Feeding pelleted dehydrated alfalfa could help to reduce the incidence and severity of GGD.

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Section: Discussionmentioning

confidence: 50%

Section: Discussionmentioning

confidence: 99%