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Abstract

The objective of chronotherapy is to optimize medical treatments taking into account the body's circadian rhythms. Drug delivery systems that precisely control the release rates or target drugs to a specific site have an enormous impact on the health care system. Over the past few years, pharmaceutical industry has focused its research in the development of various Chrono therapeutic delivery systems. By choosing the optimal time to achieve the desired effect, treatment opportunities may arise, and undesirable side effects minimized. Hence, the long-term interest of both the public and the industry is to develop new and more effective methods on the current study focus -Chrono pharmaceuticals. The present article covers findings about the effects of biorhythms on various disorders, and their implications for drug therapy and also the design of novel chrono pharmaceutical drug delivery systems that might be able to release the therapeutic agents at predetermined intervals.