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Kırnap, Mahir; Soy, Ebru H. Ayvazoglu; Özçay, Figen; Moray, Gökhan; Özdemir, Binnaz Handan; Haberal, Mehmet

doi:10.6002/ect.mesot2016.o29

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…Barrena et al [106] , 2011 15 1991-2009 1-5-10 years: 93.3% ± 6.4% 4.8 ± 2.9 years Cruz et al McAteer et al [12] , 2013 53 1998-2009 5 years: 86.5%…”

Section: Years (1-5 Years)mentioning

confidence: 98%

A practical approach to pediatric liver transplantation in hepatoblastoma and hepatocellular carcinoma

Calinescu¹,

Hery²,

Goyet³

et al. 2021

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Progressively, as chemotherapy has become more effective, more children with liver malignancies are amenable to liver transplantation, and indications have expanded from a limited range of cases (mostly hepatoblastoma) to a range of other unresectable malignant liver tumors; as a result, more children with hepatocellular carcinoma are also now proposed to transplantation, even and often outside the Milan criteria, for a cure. Recent series have highlighted that patient and graft survivals after transplantation for hepatoblastoma and hepatocellular carcinoma have improved in the last decade. Although consensus has not yet been reached about transplantation as a possible cure for other tumor types than hepatoblastoma and hepatocellular carcinoma, liver transplantation, generally speaking, has become an important pillar in the management of pediatric liver malignancies. Remaining limitations and inquiries relate to patient selection (in term of selection criteria considering the risk of recurrence), the role and usefulness of chemotherapy after transplantation, or the best immunosuppression strategy to both protect renal function and improve outcome. Although some prospective studies are on the way regarding these aspects, more studies are needed to explore this rapidly changing aspect of care.

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“…Barrena et al [106] , 2011 15 1991-2009 1-5-10 years: 93.3% ± 6.4% 4.8 ± 2.9 years Cruz et al McAteer et al [12] , 2013 53 1998-2009 5 years: 86.5%…”

Section: Years (1-5 Years)mentioning

confidence: 98%

A practical approach to pediatric liver transplantation in hepatoblastoma and hepatocellular carcinoma

Calinescu¹,

Hery²,

Goyet³

et al. 2021

View full text Add to dashboard Cite

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A single-center retrospective analysis of childhood hepatoblastoma in China

Xiang

et al. 2020

Gland Surg

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Background: This study aimed to investigate the critical factors associated with prognosis for children with hepatoblastoma (HB) in mainland China combined with the aspect of health economics and management.Methods: This study retrospectively reviewed children with HB in Renji Hospital Affiliated to the Shanghai Jiao Tong University School of Medicine from January 2013 to December 2019. Descriptive analysis was used to describe the essential characteristics. Kaplan-Meier method and Cox proportional hazard models were used to estimate the survival rate and prognosis factors.Results: For the 87 children with HB, the average survival was 2,002.8 days (95% CI: 1,798.7-2,206.9 days), the 1-and 5-year survival rates were 87.7% and 78.9%, respectively. Undergoing surgery and sex were independent prognostic factors of childhood HB. Children with HB undergoing hepatectomy (HR: 0.039) or liver transplantation (HR: 0.142) had a better prognosis, while boys were associated with a poorer prognosis (HR: 3.614). The average medical expenses for childhood HB were 40,217.5±3,862.0 CNY and liver transplantation cost more than hepatectomy. Conclusions:The results had a comparable survival rate with other studies globally. Surgical therapy and sex are associated with the prognosis of children with HB. The economic burden of childhood HB deserves to be further explored.

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