6β-Hydroxyeremophil-7(11)-en-8β,12-olide

Abstract

The title eremophilenolide, C15H22O3, is a natural compound isolated from Senecio laetus Edgew. The two cis-fused six-membered rings have chair confomations and the five-membered ring has a planar envelope conformation [maximum deviation = 0.010 (1) Å]. The β-hy­droxy group participates in inter­molecular O—H⋯O hydrogen bonding, forming mol­ecular chains along the a axis.

Natural sesquiterpenoids

“…The structure of the lactone 404 has been determined by X-ray analysis. 348 Two new bakkenolides, valerilactone A 405 and valerilactone B 406, have been isolated from Valeriana jatamansi. 349 Another compound of this type, bakkenolide VI 407, has been found in an extract of the rhizomes of Petasitis tatewakianus.…”

“…348 Two new bakkenolides, valerilactone A 405 and valerilactone B 406, have been isolated from Valeriana The relative structure of the known sesquiterpene (+)-dioxosarcoguaiacol 430 has been established. 348 Two new bakkenolides, valerilactone A 405 and valerilactone B 406, have been isolated from Valeriana The relative structure of the known sesquiterpene (+)-dioxosarcoguaiacol 430 has been established.…”