74 Sleep Apnea (SA) is an Effect Modifier of Associations of Diabetes Mellitus (DM) on Albuminuria and Cardiovascular Disease (CVD): NHANES

Dadi, Neelakanta; Wei, Guo; Unruh, Mark; Greene, Tom; Baird, Bradley C.; Beddhu, Srinivasan

doi:10.1053/j.ajkd.2011.02.077

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“…One of the excluded studies, the Nutritional Health And Nutrition Examination Survey (NHANES) study, was published as a conference abstract. 25 The study was excluded because only 9.5% of the participants were diabetic, and it was unclear whether the self-reported sleep apnea was central or OSA. Multivariate regression analysis demonstrated that when DM and sleep apnea coexist, the risk of micro-albuminuria was three-fold higher (OR 3.4, 95% CI: 1.80-6.39) and risk of macro-albuminuria was 11 times greater (OR 11.39, 95% CI: 4.60-28.42) after adjusting for confounders.…”

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confidence: 99%