766 a Panel of Gene Expression Biomarkers Predicting Sustained Virologic Response (Svr) in Chronic Hepatitis C Patients (Ch-C) Treated With Pegylated Interferon Alpha and Ribavirin
“…Blood samples for mRNA profiling were collected in three PAXgene ™ RNA blood tubes (PreAnalytiX GmbH, a Qiagen/BD Company, Switzerland). Gene expression profiling followed a previously reported protocol (22). Total RNA from each PAXgene ™ RNA blood tube was extracted, pooled and quantified with the RiboGreen ™ quantitation kit (Invitrogen, Carlsbad, CA, USA).…”
Gene expression might predict moderate to severe hepatic steatosis, NASH and fibrosis in patients with CH-C, providing potential insights into the pathogenesis of hepatic steatosis and fibrosis in these patients.
“…Blood samples for mRNA profiling were collected in three PAXgene ™ RNA blood tubes (PreAnalytiX GmbH, a Qiagen/BD Company, Switzerland). Gene expression profiling followed a previously reported protocol (22). Total RNA from each PAXgene ™ RNA blood tube was extracted, pooled and quantified with the RiboGreen ™ quantitation kit (Invitrogen, Carlsbad, CA, USA).…”
Gene expression might predict moderate to severe hepatic steatosis, NASH and fibrosis in patients with CH-C, providing potential insights into the pathogenesis of hepatic steatosis and fibrosis in these patients.
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