2022
DOI: 10.1093/eurheartjsupp/suac121.332
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851 Repeatability of Bolus and Continuous Thermodilution for Assessing Coronary Microvascular Function

Abstract: Introduction The bolus thermodilution-derived index of microcirculatory resistance (IMR) has emerged over years as the standard of reference to invasively define coronary microvascular dysfunction (CMD). However, the technique still presents some limitations, mainly related to the fact that manual injection of saline bolus accounts for some variance in the measurements. Continuous intracoronary thermodilution has been recently introduced as a tool to directly quantify absolute coronary flow a… Show more

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Cited by 2 publications
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“…Bolus thermodilution is an operator‐dependent technique; the position of the guiding catheter, the location of the temperature sensor, and the injection technique have been shown to affect the results. Moreover, it has been shown that the coefficient of variation of resistance measurements derived can be as high as 24%; these may have introduced errors in the measurement affecting the agreement between techniques 6 …”
Section: Discussionmentioning
confidence: 99%
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“…Bolus thermodilution is an operator‐dependent technique; the position of the guiding catheter, the location of the temperature sensor, and the injection technique have been shown to affect the results. Moreover, it has been shown that the coefficient of variation of resistance measurements derived can be as high as 24%; these may have introduced errors in the measurement affecting the agreement between techniques 6 …”
Section: Discussionmentioning
confidence: 99%
“…The second method is continuous thermodilution, a volumetric approach, capable of evaluating absolute coronary blood flow ( Q , in mL/min) and microvascular resistance ( R µ , in Wood units). The latter technique has been shown to be accurate in an artificial heart model, to correlate with measurements of microvascular resistance by water ([15O] H2O) positron emission tomography (PET) in humans, and to have greater reproducibility than bolus thermodilution 4–6 …”
Section: Introductionmentioning
confidence: 99%
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