859: Laparoscopic Radioisotope Guided Pelvic Lymph Node Dissection - A Novel Technique for the Staging of Prostate Cancer

Corvin, Stefan; Eichhorn, Kai; Schlatter, Evelin; Wurm, T.; Bares, Roland; Stenzl, Arnulf

doi:10.1016/s0022-5347(18)38108-4

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2005

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“…Key work was done by Wawroschek and Harzmann providing evidence that 99m Tc-Nanocoll based sentinel node identification is highly sensitive and specific. Similar results were obtained by us in a smaller cohort [51]. Therefore, sentinel image data may be used for radiation treatment planning.…”

Section: Discussionsupporting

confidence: 87%

Intensity modulated radiotherapy for high risk prostate cancer based on sentinel node SPECT imaging for target volume definition

et al. 2005

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Background: The RTOG 94-13 trial has provided evidence that patients with high risk prostate cancer benefit from an additional radiotherapy to the pelvic nodes combined with concomitant hormonal ablation. Since lymphatic drainage of the prostate is highly variable, the optimal target volume definition for the pelvic lymph nodes is problematic. To overcome this limitation, we tested the feasibility of an intensity modulated radiation therapy (IMRT) protocol, taking under consideration the individual pelvic sentinel node drainage pattern by SPECT functional imaging.

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Section: Discussionsupporting

confidence: 87%