1995
DOI: 10.1097/00005176-199505000-00101
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91 Prevention of Oesophageal Strictures Following Ingestion of Caustics by Very High Doses of Methyl Prednisolone

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“…Upper GI endoscopy was performed in all the children within 24 hours of caustic ingestion. All patients received daily IV shots of methylprednisolone (1g/1.73 m2/day during 6 to 15 days depending on the results of the endoscopic follow‐up after one week) plus anti‐secetory drugs (anti‐H2 or omeprazole) and ampicilin plus early oral feeding resumption (Protocol of the French Working Group of Pediatric Gastroenterology, Hepatology and Nutrition (2)).…”
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confidence: 99%
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“…Upper GI endoscopy was performed in all the children within 24 hours of caustic ingestion. All patients received daily IV shots of methylprednisolone (1g/1.73 m2/day during 6 to 15 days depending on the results of the endoscopic follow‐up after one week) plus anti‐secetory drugs (anti‐H2 or omeprazole) and ampicilin plus early oral feeding resumption (Protocol of the French Working Group of Pediatric Gastroenterology, Hepatology and Nutrition (2)).…”
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confidence: 99%
“…Introduction: Prevention of caustic secondary strictures with steroids is controversed (1). Promising results have been reported with intravenous shots of high doses of methylprednisolone in a small series of children (2). The aim of this multicentric study is to assess the influence of early management of severe esophageal burns with large doses of steroids in the occurrence of esophageal stricture.…”
mentioning
confidence: 99%