945-622 Impaired Heart Rate Response to Graded Exercise: Prognostic Implications of Chronotropic Incompetence

Lauer, Michael S.; Okin, Peter M.; Larson, Martin G.; Evans, Jane C.; Anderson, Keaven M.; Lévy, Daniel

doi:10.1016/0735-1097(95)92167-4

Cited by 162 publications

(254 citation statements)

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“…Os valores de p se referem a análise ANOVA ou ANCOVA (ajustados para idade # ) para os índices, com comparação de médias pelo método de Bonferroni. mortalidade total e do risco de doença arterial coronariana 8 . Adicionalmente, em uma coorte de indivíduos assintomáticos, a presença de insuficiência cronotrópica foi previsível pelo aumento do tamanho da cavidade ventricular esquerda e, nos homens, pela depressão da fração de ejeção do ventrículo esquerdo 7 .…”

Section: Discussionunclassified

“…A insuficiência cronotrópica (ICr) é caracterizada como a incapacidade de aumentar a freqüência cardíaca (FC) durante o teste ergométrico (TE) e está claramente relacionada com o pior prognóstico dos pacientes com coronariopatia 8 . Embora a ICr seja um evento relativamente comum em pacientes chagásicos, sua importância na evolução destes é ainda pouco conhecida 5 6 9 12 .…”

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Índice cronotrópico-metabólico na doença de Chagas

Rocha

Teixeira

et al. 2005

Rev. Soc. Bras. Med. Trop.

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Section: Discussionunclassified

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Índice cronotrópico-metabólico na doença de Chagas

Rocha

Teixeira

et al. 2005

Rev. Soc. Bras. Med. Trop.

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“…However, the android group showed higher values of SPB and DPB during rest as well as lower HRmax. The lower HRmax for the android group may indicate a compensatory mechanism of depressed chronotropic responses [32]. In this context, autonomic nervous control of the heart rate could be analyzed in the future, as depressed autonomic responses have been observed in arterial hypertension [33].…”

Section: Discussionmentioning

confidence: 99%

Impact of fat distribution on metabolic, cardiovascular and symptomatic aspects in postmenopausal women

Paolillo

Milan

Paolillo

et al. 2013

Int J Diabetes Dev Ctries

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The aim of this study was to investigate the anthropometric, metabolic, cardiovascular and symptomatic profile in gynoid and android postmenopausal women. Forty five postmenopausal women aged 50 to 60 years were divided into two groups according to fat distribution [waist-to-hip ratio (WHR)]: gynoid group (WHR between 0.68 and 0.8; N=13) and android group (WHR>0.8; N= 32). Body composition, skinfold thickness, serum/plasma estradiol, creatinine, urea, lipid profile, glucose and insulin, maximal exercise testing and menopause rating scale (MRS) were evaluated. The android group when compared to the gynoid group showed (P<0.05): (i) higher values of body mass, BMI, waist circumference, body fat, lean mass and skinfold thickness; (ii) higher values of estradiol, triglycerides, very low-density lipoprotein (VLDL) and insulin levels with lower insulin sensitivity (%S) and greater insulin resistance (%IR) index; (iii) higher blood pressure (BP) during rest and lower maximal heart rate (HRmax) during maximal exercise testing and; (iv) higher scores of the somatic and urogenital-sexual symptoms. This study suggests that android postmenopausal women develop features that can lead to metabolic syndrome (MetS) and future cardiovascular disease (CVD), and these women may present higher scores of somatic and urogenital-sexual symptoms.

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“…The inability to adequately increase maximum heart rate is called CI and it has been reported that CI is related to mortality and morbidity in a non disabled population (Lauer et al, 1996). Initially it was thought that CI is only influenced by autonomic dysfunction Fernhall et al, 2001 b ;Guerra et al, 2002).…”

Section: Cardiovascular Factorsmentioning

confidence: 99%

The functional fitness capacity of adults with Down syndrome in South Africa

Terblanche

Boer

2012

J intellect Disabil Res

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Background It is well established that there is a relationship between physical inactivity and increased risk for diseases of lifestyle. Persons with Down syndrome (DS) are especially at risk because of physical and health impairments, as well as perceived and real barriers to participation in exercise. The purpose of the study was to establish the functional fitness capacity and predictors of performance of DS adults. Methods Data were collected at various intellectual disability centres and private homes in seven provinces of South Africa. Three hundred and seventy‐one DS individuals (199 men and 172 women) from 18 to 66 years were tested for balance, flexibility, coordination, muscular strength and endurance, aerobic capacity and functional ability. Data were categorised according to gender and age groups (18–25, 26–35, 36–45, and >45 years). Multiple regression analysis was performed to determine the relationship between the functional task and physical test items. Results Down syndrome men performed significantly better on all but two tests compared with the women (P < 0.05). DS women performed better on the sit‐and‐reach flexibility item and the chair stand test; however, differences were not statistically significant from the men. Significant differences across age groups were observed for nine of the 13 functional fitness tests (P < 0.05). Muscular strength items, especially leg strength, significantly predicted functional performance in DS men and women. Aerobic capacity only predicted functional performance in DS men and sit‐and‐reach flexibility and dynamic balance only in DS women. Conclusions Findings of this study provide important information on the functional capacity of DS adults and show which physical attributes contribute to functional performance. Consequently appropriate training programmes can be tailored for this population whom is known to have poor functional fitness.

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945-622 Impaired Heart Rate Response to Graded Exercise: Prognostic Implications of Chronotropic Incompetence

Cited by 162 publications

References 0 publications

Índice cronotrópico-metabólico na doença de Chagas

Índice cronotrópico-metabólico na doença de Chagas

Impact of fat distribution on metabolic, cardiovascular and symptomatic aspects in postmenopausal women

The functional fitness capacity of adults with Down syndrome in South Africa

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