966 The Nonthyroidal Illness Syndrome in Septic Children

Neamţu, Bogdan; Neamtu, ML; Neamtu, C Berghea; Diac, FS

doi:10.1136/archdischild-2012-302724.0966

Cited by 3 publications

(3 citation statements)

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“…Euthyroid sick syndrome prevalence has been reported to have increased by aging particularly in critically ill elderly patients. Moreover, ESS has been associated with poor prognosis, the development of complications, severity of disease, and mortality in older subjects, particularly in critically ill geriatric patients (14 (17). Supporting this in our study, the total ESS prevalence was 84.2%, 108 of which (88.5%) were in the geriatric group and 63 (77.8%) were in the control group.…”

Section: Discussionsupporting

confidence: 82%

Euthyroid Sick Syndrome: Prevalence and Prognosis in Elderly Patients With Sepsis

Cakmak¹,

Atıcı²,

Bektaş³

et al. 2022

jmed

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Objective: Euthyroid sick syndrome (ESS) manifests by the decreased level of serum free thyroid hormones and with the normal or decreased secretion of thyroid-stimulating hormone. The study aims to identify the prevalence of ESS in elderly patients with sepsis and evaluate its possible effect on prognosis and mortality.Material and Methods: Two hundred and three patients diagnosed with sepsis were prospectively evaluated. They were divided into two groups, a geriatric group (≥65 years), and a control group (<65 years). Patients with low free T3 (fT3) and/or free T4 (fT4) were considered to have euthyroid-sick syndrome. The demographic characteristics, comorbidities, laboratory results, hospitalization data, intensive care unit (ICU) duration, treatment outcomes, and mortality rates of the patients were recorded and compared.Euthyroid sick syndrome: prevalence and prognosis in sepsis İstanbul Tıp Fakültesi Dergisi • J Ist Faculty Med Conclusions: The higher prevalence of ESS (88.5%) in elderly patients with sepsis was clearly demonstrated. Additionally, approximately two-fold higher mortality and ICU stay risk was documented in the ESS (+) group. Thus, simply screening of ESS in septic elderly patients will certainly contribute to treatment decisions and early prediction of complicated clinical course and poor prognosis.

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Section: Discussionsupporting

confidence: 82%

Euthyroid Sick Syndrome: Prevalence and Prognosis in Elderly Patients With Sepsis

Cakmak¹,

Atıcı²,

Bektaş³

et al. 2022

jmed

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show abstract

“…In the prospective study by Neamtu et al [14] on 65 children with sepsis, T3 and T4 levels were found to be low in 63% of the patients. In a study conducted by Lodha et al [12] that evaluated 24 children either with sepsis or in septic shock, lower fT3, fT4, and TSH levels were found in patients in septic shock compared to patients in a less severe septic state.…”

Section: Discussionmentioning

confidence: 92%

Non-thyroid disease syndrome: a strong prognostic predictor of death in patients with pneumonia

Bora¹,

Çakır²,

Hacar³

et al. 2021

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Introduction: Non-thyroid disease syndrome (NTDS) is a common syndrome in critical diseases and is characterized by below-normal levels of free T3 (fT3) and free T4 (fT4) in the absence of primary thyroid gland pathology. Pneumonias are a group of respiratory system infections that are associated with a high incidence of mortality. Rapid biomarkers are needed to determine the diagnosis and prognosis in patients with pneumonia to optimize treatment potential. This study investigated the effect of changes in thyroid hormone and procalcitonin (PCT) levels on prognosis and mortality in patients with pneumonia. Method: This study was conducted as a retrospective observational study in a tertiary hospital. Between 2019 and 2020, 1118 patients with pneumonia were included in the study. For all participants, PSI scores were calculated and disease severity was determined according to these scores. Patient demographic and disease data were recorded. Discussion and Conclusion: Low fT3 hormone levels in patients diagnosed with pneumonia upon arrival at the emergency department had an important effect on prognosis. Our results indicated that fT3 levels had a reliable predictive effect on prognosis, disease severity, and mortality. In addition, we found that fT3 was superior to PCT in predicting mortality.

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“…Neamtu et al ., prospectively studied 65 children with sepsis, and found that 63% of children with sepsis had “low T3-T4” syndrome, which is close to our study. [ 20 ]…”

Section: Discussionmentioning

confidence: 99%

Prognostic significance of nonthyroidal illness syndrome in critically ill adult patients with sepsis

Padhi¹,

Kabi²,

Panda³

et al. 2018

Int J Crit Illn Inj Sci

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966 The Nonthyroidal Illness Syndrome in Septic Children

Cited by 3 publications

References 0 publications

Euthyroid Sick Syndrome: Prevalence and Prognosis in Elderly Patients With Sepsis

Euthyroid Sick Syndrome: Prevalence and Prognosis in Elderly Patients With Sepsis

Non-thyroid disease syndrome: a strong prognostic predictor of death in patients with pneumonia

Prognostic significance of nonthyroidal illness syndrome in critically ill adult patients with sepsis

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