99mTc-glucoheptonate for quantitation of differential renal function

Ziessman, H.A.; Balseiro, J; Fahey, FH; Le, TV; Dubiansky, V

doi:10.2214/ajr.148.5.889

Cited by 6 publications

(1 citation statement)

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“…The typical administered activity of 131 I-iodohippurate was 9.25 MBq (Mettler and Guiberteau 1983, 1998; Mettler et al 1986). Typical administered activities of 99m Tc-DTPA and 99m Tc-GH varied between 370 MBq and 555 MBq; while the typical administered activities of 99m Tc-DMSA and 99m Tc-MAG3 were 185 MBq and 370 MBq, respectively (Enlander et al 1974; USDHEW, 1976; Shanahan and Klingensmith 1981; Robertson 1982; Mettler and Guiberteau 1983, 1998, 2012; Schultz et al 1985; Ziessman et al 1987; Setaro et al 1991; Barbaric 1994; Wagner et al 1995; Mandell et al 1999; Kowalsky and Falen 2004; Dahnert 2007; Mettler et al 2008a; 2008b; NCRP 2009; Jafari and Daus. 2013).…”

Section: Resultsmentioning

confidence: 99%

Use of Radiopharmaceuticals in Diagnostic Nuclear Medicine in the United States

Drozdovitch¹,

Brill²,

Callahan³

et al. 2015

Health Physics

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To reconstruct reliable nuclear medicine-related occupational radiation doses or doses received as patients from radiopharmaceuticals over the last five decades, we assessed which radiopharmaceuticals were used in different time periods, their relative frequency of use, and typical values of the administered activity. This paper presents data on the changing patterns of clinical use of radiopharmaceuticals and documents the range of activity administered to adult patients undergoing diagnostic nuclear medicine procedures in the U.S. between 1960 and 2010. Data are presented for 15 diagnostic imaging procedures that include thyroid scan and thyroid uptake, brain scan, brain blood flow, lung perfusion and ventilation, bone, liver, hepatobiliary, bone marrow, pancreas, and kidney scans, cardiac imaging procedures, tumor localization studies, localization of gastrointestinal bleeding, and non-imaging studies of blood volume and iron metabolism. Data on the relative use of radiopharmaceuticals were collected using key informant interviews and comprehensive literature reviews of typical administered activities of these diagnostic nuclear medicine studies. Responses of key informants on relative use of radiopharmaceuticals are in agreement with published literature. Results of this study will be used for retrospective reconstruction of occupational and personal medical radiation doses from diagnostic radiopharmaceuticals to members of the U.S. radiologic technologist’s cohort and in reconstructing radiation doses from occupational or patient radiation exposures to other U.S. workers or patient populations.

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Section: Resultsmentioning

confidence: 99%

Use of Radiopharmaceuticals in Diagnostic Nuclear Medicine in the United States

Drozdovitch¹,

Brill²,

Callahan³

et al. 2015

Health Physics

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Radionuclide quantitation of renal function

Sanger

Kramer

1992

Urol Radiol

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Quantitation of renal function may be performed with a variety of radiopharmaceuticals which reflect slightly different renal functions. Plasma sampling techniques and imaging techniques have been used to derive absolute measurements of renal function. The addition of imaging permits the determination of relative or "split" function. Time-activity curves from renal studies provide other quantitative parameters of function reflecting arterial supply, renal cortical function, and patency of the renal collecting system. Quantitative radionuclide studies of the kidneys provide comprehensive, reproducible, and objective assessments of renal function.

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