9A.04

Erba, Giuseppe; Grosso, Giorgia; Valena, C.; Riva, M.; Allevi, E.; Betelli, Mauro; Facchetti, Rita; Mancia, Giuseppe; Pozzi, Maria Rosa

doi:10.1097/01.hjh.0000467667.84403.7d

Cited by 3 publications

(2 citation statements)

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“…For instance, we identi ed a much higher prevalence of cigarette smoking in the RA group than in the OA group or general population. Further, all the groups had a similar prevalence of hypertension (after standardization), which is in disagreement with some previous studies [30,[53][54][55][56][57][58]. We cannot fully explain the higher prevalence of smoking in patients with RA because smoking aggravates RA symptoms, but also may have bene cial psychological effect, especially on those with high stress from chronic disease, or pain.…”

Section: Discussioncontrasting

confidence: 81%

“…Upgrades SCORE2 and SCORE2-OP (older persons), published in 2021 estimate the risk of fatal and non-fatal CV events in people aged 40-69 years with no known CVD, and different values are assigned for low-, moderate-, high-, and very high-risk countries [27][28][29]. Because RA increases CV risk in addition to other risk factors, studies have recommended that the calculated relative risk is multiplied by 1.4 for men and 1.5 for women if two of the three following RA criteria are met: (1) disease duration > 10 years, (2) rheumatoid factor (RF) or anti-citrulline antibody (anti-CCP) positivity, and (3) the presence of extra-articular manifestations (Felty's syndrome, pericarditis, pleuritis, polyneuropathy, mononeuritis, episcleritis, glomerulonephritis, or skin or other organ vasculitis) [27][28][29][30]. Despite SCORE modi cations, limitations to CV risk estimation and early atherosclerosis detection remain [31].…”

Section: Introductionmentioning

confidence: 99%

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Risk for cardiovascular disease development in rheumatoid arthritis

Bedeković,

Bošnjak,

Bilić-Ćurčić

et al. 2023

Preprint

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Background Patients with rheumatoid arthritis have significant cardiovascular mortality and morbidity. Objective To investigate the effects of chronic inflammation in rheumatoid arthritis on cardiovascular morbidity association with cardiovascular risk factors risk factors. Mortality report is secondary just to show trends without sufficient statistical power as it is accidental endpoint. Methods A total of 201 individuals without previous cardiovascular disease, 124 with rheumatoid arthritis (investigation group) and 77 with osteoarthritis (control group), were included in the study and followed up for an average of 8 years to assess the development of fatal or non-fatal cardiovascular diseases. The incidence and prevalence of cardiovascular risk factors were also investigated. Results The total incidence of one or more fatal or nonfatal cardiovascular events was 43.9% in the investigation group and 37.5% in the control group. Of these patients, 31.7% and 30.9% survived cardiovascular events in the investigation and control groups, respectively. The most common cardiovascular disease among participants who completed the study and those who died during the study was chronic heart failure. The results of the subgroup analysis showed that strict inflammation control plays a central role in lowering cardiovascular risk.. Conclusion A multidisciplinary approach to these patients is of paramount importance, especially with the cooperation of immunologists and cardiologists for early detection, prevention, and management of cardiovascular risks and diseases.

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Section: Discussioncontrasting

confidence: 81%

Section: Introductionmentioning

confidence: 99%

Risk for cardiovascular disease development in rheumatoid arthritis

Bedeković,

Bošnjak,

Bilić-Ćurčić

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

Risk for cardiovascular disease development in rheumatoid arthritis

Bedeković,

Bošnjak,

Bilić-Ćurčić

et al. 2024

BMC Cardiovasc Disord

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Background Patients with rheumatoid arthritis have significant cardiovascular mortality and morbidity. Objective To investigate the effects of chronic inflammation in rheumatoid arthritis on cardiovascular morbidity association with cardiovascular risk factors risk factors. Mortality report is secondary just to show trends without sufficient statistical power as it is accidental endpoint. Methods A total of 201 individuals without previous cardiovascular disease, 124 with rheumatoid arthritis (investigation group) and 77 with osteoarthritis (control group), were included in the study and followed up for an average of 8 years to assess the development of fatal or non-fatal cardiovascular diseases. The incidence and prevalence of cardiovascular risk factors were also investigated. Results The total incidence of one or more fatal or nonfatal cardiovascular events was 43.9% in the investigation group and 37.5% in the control group. Of these patients, 31.7% and 30.9% survived cardiovascular events in the investigation and control groups, respectively. The most common cardiovascular disease among participants who completed the study and those who died during the study was chronic heart failure. The results of the subgroup analysis showed that strict inflammation control plays a central role in lowering cardiovascular risk. Conclusion A multidisciplinary approach to these patients is of paramount importance, especially with the cooperation of immunologists and cardiologists for early detection, prevention, and management of cardiovascular risks and diseases.

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Cardiac involvement in some rheumatic diseases.

Фейсханова

Khaliullina

2018

Klin. med.

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The review covers the modern scientific literature about cardiovascular disease in patients with rheumatic diseases. Rheumatic diseases are associated with chronic inflammation, most often joints, skin, eyes, lungs, kidneys and circulatory system. Cardiovascular manifestations of autoimmune diseases can be mild and clinically silent; they can also increase morbidity and mortality. Defeat of cardiovascular system at patients with rheumatoid arthritis: myocarditis, a pericarditis, myocardial fibrosis, ventricular arrhythmias, a syndrome of the extended interval of QT, atrial fibrillation, valvulopathy, development of chronic heart failure, formation of heart disease. Cardiac involvement in systemic lupus erythematosus follows different pathophysiologic mechanisms and covers a wide spectrum of clinical phenotypes including pericarditis, myocarditis, valvular abnormalities, aseptic endocarditis, heartfailure, ischaemic heart disease and pulmonary hypertension. Valvular disease in systemic lupus erythematosus includes valvulitis, aortic and mitral regurgitation, aortic stenosis. For diagnosis of cardiovascular diseases are used clinical laboratory methods, the electrocardiogram, echocardiography, single-photon emission computed tomography, positron emission tomography/ computed tomography, computed coronary angiography, computed tomography, magnetic resonance imaging. The following echocardiographic abnormalities have been reported in ankylosing spondylitis: ascending aortitis, aortic and mitral regurgitation, mitral valve prolapse and diastolic dysfunction. The following echocardiographic abnormalities can be seen in psoriatic arthritis: fibrinous pericarditis, myocarditis and valvular disease.

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9A.04

Cited by 3 publications

References 0 publications

Risk for cardiovascular disease development in rheumatoid arthritis

Risk for cardiovascular disease development in rheumatoid arthritis

Risk for cardiovascular disease development in rheumatoid arthritis

Cardiac involvement in some rheumatic diseases.

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