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Abstract

Background: Reduced fertilization and implantation rates have been recognized by various research efforts to be a critical issue in cases of teratospermia, globospermia, and megalospermia affecting the IVF-ICSI management cycles rates of success. A real-time and high-magnification technique for selection of sperms together using a micromanipulation technique named intracytoplasmic morphologically selected sperm injection was observed by prior research efforts to have higher effectiveness than the traditional intracytoplasmic sperm injection Aim: to investigate the detailed sperm morphological features affect the outcome of intracytoplasmic sperm injection (ICSI).Methodology: The research study cohort was composed of the male partners of 140 random couples referred for ICSI treatment Inclusive research criteria involved females younger than 37 years old and more than 3 retrieved ovum per management cycle. ICSI Procedure: Indications for ICSI have been as follows poor (less than 20%) or no (0%) fertilization in the first IVF cycle, immotile sperms, and low percentage of normally formed sperms (less than 4%) the motile sperm fractions have been prepared for ICSI management cycle from sperm ejaculated using the swim-up method cases of oligospermia (sperm concentration less than 15 *106 sperms /mL the densitygradient technique was used .Sperm selection for microinjection was conducted at a magnification of 200*400 the embryologist have excluded sperms from microinjection into the ovum those having severe head-shape abnormalities Result: Receiver operating characteristic curve (ROC) for MSOME (%) as a predictors of (A) normal fertilization as regards normal spermatozoa at cut off point >2, AUC =0.