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Abstract

The majority of benzodiazepines is administered orally and has various beneficial effects, including psychotropic, anxiolytic, hypnotic, sedative, muscle relaxing, anticonvulsant, and amnesic ones. These include benefits for alcohol dependence, epileptic seizures, irritable disorders, scare, and insomnia. The goal of this study was to create bicycles from benzodiazepines through cyclization steps. All generated compounds were examined by using several analytical techniques, including: FT-IR, 1 H-NMR, Mass spectroscopy analysis, and other chemical characterization, with formatted compounds being assessed as antifungals and inhibitors. These compounds were utilized to explain biological activity against "Aspergilla's and Candida" albicans at various concentrations (5, 10, 15, and 20 mg/ml -1 ). The findings demonstrated that all compounds were active against all varieties of fungi and that oxazepine, diazepine bicycles, and heteroatoms in the structure inhibited the corrosion of mild steel in 0.5M HCl.

Preparation and Analysis of Heterocyclic Rings Made from (Thioxanthone) Derivatives Methods of Biological Activity, Thermal Analysis

“…Heterocyclic rings are cyclic compounds (organic ) have contain one or more hetero atoms in structures, are (nitrogen, oxygen and sulphur) [1]. Most drugs are derivatives from heterocyclic compounds played widely role in living cells, DNA and RNA, hemoglobin and vitamins as (β-Lactams and Imidazole ) [2].…”

“…Aseel Fadhil Kareem1 , Amal Talib Al Sa'ady2 1 Dept. of Pharmaceutical Chemistry, College of Pharmacy, University of Babylon, Iraq.…”