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Abstract

Buckwheat has been a major food source in Asian countries such as China, Japan, and Bhutan etc. for its nutritional values. It has been a major functional food supplement for nutraceutical industry. It is the first time exploration of buckwheat seed powder as tablet binder. The aim the study was to expand the area off tablet binders from gums and extracted polysaccharides to whole seed powders so as to reduce processing cost involved with other synthetic binders and involvement of whole seed benefits to single dosage form. In the present study buckwheat seed powder was used in the concentrations of 1%, 2%, 4%, 6% and it was compared with binding capacity of 2.5% acacia in tablet formulation as direct compressible agent. Valsartan was used as a model drug. It was found out that 2% w/w concentration of Buckwheat seed powder performed well and all the parameters were in good range. It was concluded that buckwheat seed powder can be a good direct compressible agent for tablet formulation.