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Toda, Riichiro; Yotsumoto, Goichi; Masuda, Hiroshi; Sakata, Ryuzo; Umekita, Yoshihisa

doi:10.1007/s005950200034

Cited by 13 publications

(1 citation statement)

References 28 publications

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“…Rather, molecular alterations in individual cases of MFH seem to be responsible. By 2002, there were only 42 cases of patients with primary cardiac MFH, of whom the youngest patient was 16 years old [76]. …”

Section: Primary Cardiac Sarcomamentioning

confidence: 99%

State of the art paper Sarcomas of the heart as a difficult interdisciplinary problem

Ostrowski¹,

Marcinkiewicz²,

Kośmider³

et al. 2014

aoms

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Cardiac tumors are assumed to be a rare entity. Metastases to the heart are more frequent than primary lesions. Sarcomas make up the majority of cardiac malignant neoplasms. Among them angiosarcoma is the most common and associated with the worst prognosis. Malignant fibrous histiocytoma comprises the minority of cardiac sarcomas and has uncertain etiology as well as pathogenesis. Transthoracic echocardiography remains the widely available screening examination for the initial diagnosis of a cardiac tumor. The clinical presentation is non-specific and the diagnosis is established usually at an advanced stage of the disease. Sarcomas spread preferentially through blood due to their immature vessels without endothelial lining. Surgery remains the method of choice for treatment. Radicalness of the excision is still the most valuable prognostic factor. Adjuvant therapy is unlikely to be effective. The management of cardiac sarcomas must be individualized due to their rarity and significant differences in the course of disease.

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Section: Primary Cardiac Sarcomamentioning

confidence: 99%

State of the art paper Sarcomas of the heart as a difficult interdisciplinary problem

Ostrowski¹,

Marcinkiewicz²,

Kośmider³

et al. 2014

aoms

View full text Add to dashboard Cite

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Malignant Fibrous Histiocytoma of the Abdominal Cavity: Report of a Case

et al. 2003

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Malignant fibrous histiocytoma (MFH) is a soft-tissue sarcoma originating from fibroblast cells, characterized by a high rate of metastasis or recurrence. This tumor rarely develops in the gastrointestinal tract, with no more than 30 cases described in the literature. We report a case of MFH of the abdominal cavity in a 45-year-old woman who presented with epigastric pain, anorexia, and weight loss. A computed tomography (CT) scan of the abdomen revealed multiple solid tumors in the peritoneal cavity. We performed exploratory laparotomy and found at least 15 solid whitish tumors attached to the wall of the small intestine, as well as to the parietal peritoneum. There were three metastases in the liver. All of the tumors were excised, most of which were about 10 cm in diameter. Histopathological findings indicated a stromal tumor consisting of spindle cells, and immunohistochemical examination of the resected specimens established the definite diagnosis of a pleomorphic MFH. The patient had an uneventful postoperative course and was given adjuvant chemotherapy. She is currently well 2 years after her operation. We review the clinical picture of this tumor in the abdominal cavity, and discuss its diagnosis, pathogenesis, and treatment.

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