Concentrations of five heavy metals (Hg, Cd, Pb, Cu and Zn) in edible tissues of four fish species (Cyprinus carpio, Platichthys flesus, Liza aurata, Mugil cephalus) collected from Natural Reserve Area called Sarikum Lake were determined by ICP-MS (Agilent 7700x). The order of heavy metal concentration was observed as: Zn> Cu > Hg > Pb > Cd. The heavy metal levels were species specific and significantly different. The highest concentrations of Hg, Cd and Zn were found in flathead grey mullet, European flounder and common carp, respectively. The higher concentrations of Pb and Cu are present in golden grey mullet. The concentrations of Cd are in range of 0.019-0.027 µg g-1 in common carp, 0.028–0.040 µg g-1 in European flounder, 0.020-0.034 µg g-1 in golden grey mullet and 0.16-0.27 µg g-1 in flathead grey mullet tissues. Concentration of Cd in M. cephalus was limit value and precautions need to be taken in order to prevent future heavy metal contamination, but other metals were lower than those in certified values. Keywords: Cyprinus carpio, Platichthys flesus, Liza aurata, Mugil cephalus, Sarikum Lake