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Abstract

ABSTRACT:The aim of this study were to synthesize and antimitotic activity of the cyanoacetyl hydrazones derivatives. The synthesized compounds were subjected to antimitotic studies by alliumcepa root meristamatic cells. The mitotic activity was observed in various concentrations of cyanoacetyl hydrazones. Antimitotic -activity of the synthesized compounds were observed in higher concentrations. Antimitotic activity of cyanoacetyl hydrazones were dose dependent.Increase in the concentrations is directly proportional to the activity.