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Abstract

Porpouse: Analyze the incidence of persistence and recurrence of ovarian endometriomas in patients at a reference center and evaluate possible associated factors.Methods: A cohort study with patients histologically diagnosed with ovarian endometriomas, attended at a reference center for endometriosis and pelvic chronic pain at State Public Servants Hospital -Francisco Morato de Oliveira, from 01/01/2003 to 01/07/2019. Follow up was registered in clinical charts, from which we analyzed epidemiological data, characteristics of the disease, type of surgery, medical treatment, its interruption and follow up time. A logistic regression model was used to evaluate predictors associated with persistence and recurrence, separately. Results:We analysed data from 293 patients, with a median follow up time of 74.16 months (40.26 -112.73). Persistence was found in 9.87% (37) of patients after surgery and overall rate of recurrence was 20.27% (77). "Drainage of endometriomas" and "GnRH agonist use" were both correlated to persistence, OR: 9.09 (3.29-25.12) and , respectively. The only predictor associated with recurrence was "interruption of clinical treatment", with OR: 5.93 (2.81-12.53) adjusted by infertility, cyst size (cm), bilaterality of cystic lesions and surgical technique of drainage. Conclusion:Ovarian endometriomas had a persistence rate of 9.87% and recurrence rate of 20.27%. Drainage of endometriotic cyst and its complementary treatment with GnRH agonist were associated with greater chance of persistence. Postoperative medical treatment's interruption was independently associated with greater chance of recurrence and inversely to time elapsed of the recurrence.