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Synthesis and Characterization of 2‐Mono‐ and 1,2‐Diaminocarba‐closo‐dodecaborates M[1‐R‐2‐H2N‐closo‐CB11H10] (R=H, Ph, H2N, CyHN)

“…[21] Its derivatives have emerged as widely used starting materials for the preparation of boron-rich compounds. [6,8,22] They have been applied for the preparation of ionic liquids with [R 3 N-closo-B 12 H 11 ] À ions (R = alkyl), [23] as building blocks in ionomers, [24] for compounds with nonlinear optical (NLO) properties, [25] as weakly coordinating anions [R 3 N-closo-B 12 F 11 ] À (R = H, alkyl), [26] as ligands in transition-metal chemistry, for example in [RuCOA C H T U N G T R E N N U N G (PPh 3 ) 2 (H 2 N-closo-B 12 H 11 )], [27] and for pharmaceuticals, [6,28] for example, for boron neutron capture therapy (BNCT). [29] Exhaustive treatment of [closo-B 12 H 12 ] 2À with H 2 NSO 3 H resulted in double substitution giving (H 3 N) 2 -closo-B 12 H 10 .…”

“…[1,68] (6). [a] B3LYP/6-311 In addition the pH dependency of the dA C H T U N G T R E N N U N G ( 13 C) signal of the cluster carbon atom and of the d( For all amino-substituted {CB 11 [69] KA…”

“…The growing interest in monocarba-closo-dodecaborates is attributed in part to their possible application in different fields, [1,2] for example as weakly coordinating anions, [3,4] in medicine, [5,6] or material sciences. [7,8] The versatility of these compounds stems from their varying and highly tunable properties, which mostly depend on the substituents attached to the cluster atoms.…”

Practical synthesis of 1,4-dioxane derivative of the closo-dodecaborate anion and its ring opening with acetylenic alkoxides

“…BNCT is a binary cancer treatment based on the interaction of two relatively harmless species, a 10 B nucleus and a thermal neutron, which results in the formation of the high-energy short-range 4 He and 7 Li particles highly energetic 4 He and 7 Li as products. The selective concentration of the 10 B nuclei within the tumor cells, followed by their capturing of thermal neutrons, should result in localized destruction of the malignant cells in the presence of the normal neighboring cells [1][2][3][4]. More recently, it was shown that the closo-dodecaborate anion could be used also as a linker for introduction of a radiohalogen label into biomolecules for radionuclide diagnostics and therapy [4][5][6][7].…”

Boron-Containing Phthalocyanines and Porphyrazines

“…[40] Water solubility of boronated phthalocyanines can be reached by change the carborane cages for the anionic dodecaborate moieties. [41,42] However, due to higher reactivity of the closo-dodecaborate [B 12 H 12 ] 2-only the first approach can be used for synthesis of boronated phthalocyanines containing the closo-dodecaborate fragments. The first highly-boronated phthalocyanines 10-13 containing the closo-dodecaborate cages were prepared by the reaction of the aminododecaborate [B 12 H 11 NH 3 ] -with chloromethyl derivatives of phthalocyanines (Scheme 7).…”